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Amplification patents



      
           
This page is updated frequently with new Amplification-related patent applications. Subscribe to the Amplification RSS feed to automatically get the update: related Amplification RSS feeds. RSS updates for this page: Amplification RSS RSS


Amplification systems and methods with one or more channels

On-bright Electronics (shanghai)

Amplification systems and methods with one or more channels

System and method for automated nucleic acid amplification

Qualcomm

Harmonic trap for common gate amplifier

Date/App# patent app List of recent Amplification-related patents
02/26/15
20150057955
 Position control  identifying low-frequency disturbance patent thumbnailnew patent Position control identifying low-frequency disturbance
A position control apparatus is provided that can perform accurate nonlinear compensation control immediately after the apparatus is activated. At a time of acceleration, a signal amplification ratio is calculated and designated for each signal vector element based on information related to acceleration/deceleration at a starting time and the structure of a signal vector that is determined for a target plant, and as a result, a signal vector for which the strength of linear independence is increased is generated.
Okuma Corporation
02/26/15
20150057168
 Primers for detecting serotypes of shigella flexneri and multiplex amplifications using the same patent thumbnailnew patent Primers for detecting serotypes of shigella flexneri and multiplex amplifications using the same
The present inventions relates to primers for identifying shigella flexneri serotypes comprising the sequences of seq id nos. 1 and 2, seq id nos.
National Institute For Communicable Disease Control And Prevention, China Cdc
02/26/15
20150056940
 Harmonic trap for common gate amplifier patent thumbnailnew patent Harmonic trap for common gate amplifier
A circuit, a method and an apparatus, are described. A radio frequency (rf) signal received from a transmission line is provided to the source of a transistor in a common-gate amplification circuit.
Qualcomm Incorporated
02/26/15
20150056663
 System and  automated nucleic acid amplification patent thumbnailnew patent System and automated nucleic acid amplification
An embodiment of a device for automatically executing a process of generating an emulsion containing nucleic acids, amplifying the nucleic acids in the emulsion, breaking the emulsion, and separating and purifying said amplified nucleic acids, is described that comprises an emulsion generation unit for sealing beads to which nucleic acids are bound in a water-in-oil type emulsion; a nucleic acid amplification unit provided with a reaction vessel for amplifying said nucleic acids and a heating and cooling part for heating and cooling the reaction vessel; an emulsion breaking unit for breaking the emulsion after nucleic acid amplification; and a nucleic acid purification unit for recovering said amplified nucleic acids from said emulsion breaking unit.. .
454 Life Sciences Corporation
02/26/15
20150056662
 System and  nucleic acid amplification patent thumbnailnew patent System and nucleic acid amplification
An embodiment of a method for generating a population of amplified concatamer products is described that comprises amplifying a template nucleic acid molecule using a first nucleic acid primer immobilized on a bead substrate and a second nucleic acid primer in solution to generate a population of substantially identical copies of the template nucleic acid molecule immobilized on the bead substrate; and amplifying the population of substantially identical copies of the template nucleic acid molecule using a concatamer primer that comprises a first region complementary to an end region of the population of substantially identical copies of the template nucleic acid molecule and a second region to generate a population of immobilized concatamer products of the substantially identical copies of the template nucleic acid molecule.. .
454 Life Sciences Corporation
02/26/15
20150056650
 Microfluidic apparatus, method, and applications patent thumbnailnew patent Microfluidic apparatus, method, and applications
A microfluidic apparatus, method, and associated applications utilize and apply to a formalin-fixed paraffin-embedded (ffpe) tissue sample and performing a liquid-liquid extraction to remove the paraffin from the tissue sample prior to a nucleic acid purification step. A microfluidic device includes a dedicated liquid-liquid extraction process vessel, a nucleic acid purification process component, and a nucleic acid amplification reactor.
Rheonix, Inc.
02/26/15
20150056626
 Nucleic acid amplification kits for specific detection of e. coli o157:h7 without co-detection of e. coli o55:h7 patent thumbnailnew patent Nucleic acid amplification kits for specific detection of e. coli o157:h7 without co-detection of e. coli o55:h7
Disclosed are assays, methods and kits for the specific detection of e. Coli o157:h7 and not e.
Life Technologies Corporation
02/26/15
20150056622
 Editing profiling of pde8a pre -mrna:  use as specific biomarker of adars activities in human tissues to diagnose and to predict and assess therapeutic efficacy and/or efficiency or potential drug side effects patent thumbnailnew patent Editing profiling of pde8a pre -mrna: use as specific biomarker of adars activities in human tissues to diagnose and to predict and assess therapeutic efficacy and/or efficiency or potential drug side effects
The present invention relates to the use of the editing profile of pde8a pre-mrna as a specific bio marker of adars activities in evolved primate, particularly in human tissues. The present invention also relates to an in vitro method for predicting in human an alteration of the mechanism of the adars catalysed pre-mrna editing of target genes, by analysing the pde8a pre-mrna editing profile in a peripheral tissue sample containing cells expressing said pde8a pre-mrna, such as blood sample.
Biocortech
02/26/15
20150056621
 Primers, methods and kits for detecting killer-cell immunoglobulin-like receptor alleles patent thumbnailnew patent Primers, methods and kits for detecting killer-cell immunoglobulin-like receptor alleles
Embodiments of the present invention describe primer pairs, methods and kits for identifying and/or detecting killer-cell immunoglobulin-like receptor (kir) alleles. The present primer sets include one or more primer pairs that can produce amplicons specific for an individual kir allele and that are less than 1000 bp in size.
Life Technologies Corporation
02/26/15
20150055732
 Power amplification system, device and method patent thumbnailnew patent Power amplification system, device and method
Embodiments of the present invention may include power amplifier architectures and systems for use in wireless communication systems. The systems may include a first circuit path for receiving an input signal and decomposing the signal into two vector signals using an out-phasing generator, modifying the vectors based on predetermined value limit, amplifying the vectors using power amplifiers, and combining the vectors to provide an amplified output.
Analog Devices Technology
02/26/15
20150055210
new patent

Ultra high power single mode fiber laser system


An ultra-high power fiber laser system includes a single-piece fiber booster configured with fiber and straight short rod fiber portions which have in common a core configured with a numerical aperture equal to or higher than 0.1 and doped with ions of one or more rare earth elements across the entire cross-section thereof. The rod fiber portion is structured with a short length not exceeding about a few tens of centimeters and has a generally frustoconical cross-section expanding from the uniformly configured fiber portion.
Ipg Photonics Corporation
02/26/15
20150054868
new patent

Liquid discharging apparatus, control method thereof, and program


There is provided a liquid discharging apparatus including: an original drive signal generation unit which generates an original drive signal; a signal modulation unit which modulates the original drive signal to generate a modulation signal; a first signal amplifying unit which amplifies the modulation signal to generate a first amplified modulation signal; a second signal amplifying unit which amplifies the modulation signal to generate a second amplified modulation signal; an amplification control unit which controls operations of the first signal amplifying unit and the second signal amplifying unit; a signal conversion unit which converts the first amplified modulation signal and the second amplified modulation signal into a drive signal; a plurality of piezoelectric elements which is deformed by the drive signal; a plurality of cavities which expands or contracts in accordance with the deformation of the plurality of piezoelectric elements; a plurality of nozzles which communicates with each of cavities.. .
Seiko Epson Corporation
02/26/15
20150054580
new patent

Amplification systems and methods with one or more channels


Systems and methods are provided for amplifying multiple input signals to generate multiple output signals. An example system includes a first channel, a second channel, and a third channel.
On-bright Electronics (shanghai) Co., Ltd.
02/26/15
20150054579
new patent

System and fast polynomial pre-distortion


A system and method for method of pre-distorting a signal applied to a power amplifier to compensate for distortion introduced by the power amplifier at different power settings, comprising pre-distorting the signal according to a pre-distortion polynomial, prior to amplification of the signal by the power amplifier; adaptively estimating and applying pre-distortion polynomial coefficients to the pre-distorter by saving successive iterations of adaptive estimation of the pre-distortion polynomial coefficients; and regularizing estimation of the pre-distortion polynomial coefficients over successive iterations according to a modified objective function that initially constrains growth in the magnitude of the pre-distortion polynomial coefficients and then relaxes the constraint in growth over successive iterations until estimation is reduced to a steady-state least squares estimation.. .
Blackberry Limited
02/26/15
20150054578
new patent

Amplification systems and methods with one or more channels


Systems and methods are provided for amplifying multiple input signals to generate multiple output signals. An example system includes a first channel, a second channel, and a third channel.
On-bright Electronics (shanghai) Co., Ltd.
02/26/15
20150054577
new patent

Amplification systems and methods with one or more channels


Systems and methods are provided for amplifying multiple input signals to generate multiple output signals. An example system includes a first channel, a second channel, and a third channel.
On-bright Electronics (shanghai) Co., Ltd.
02/26/15
20150054409
new patent

Photo sensor package for lighting


Disclosed is a photo sensor package for lighting, which is configured such that a micro control unit having a lighting control function as well as a timer function is integrated with a remote control element receiving a remote control signal of a lighting fixture. The photo sensor package includes a housing molded using infrared transmissible resin, a remote control element configured to receive an infrared signal, an amplification element configured to amplify a signal that is output from the remote control element, and a micro control unit configured to control a lighting fixture in response to a signal that is output from the amplification element.
Raytron Co., Ltd
02/26/15
20150054038
new patent

Electronic circuits including a mosfet and a dual-gate jfet


Electronic circuits and methods are provided for various applications including signal amplification. An exemplary electronic circuit comprises a mosfet and a dual-gate jfet in a cascode configuration.
Acco Semiconductor, Inc.
02/19/15
20150051099

Methods of constructing small rna libraries and their use for expression profiling of target rnas


Methods, compositions, and kits comprising target-specific oligonucleotides (tsos) are disclosed herein. Methods, compositions, and kits comprising target-specific oligonucleotides (tsos) can be used to attach adapters and/or linkers to target rnas.
Somagenics, Inc.
02/19/15
20150051092

Compositions and methods for detection of hepatitis a virus nucleic acid


Nucleic acid oligomeric sequences and in vitro nucleic acid amplification and detection methods for detecting the presence of hav rna sequences in samples are disclosed. Kits comprising nucleic acid oligomers for amplifying and detecting hav nucleic acid sequences are disclosed..
Gen-probe Incorporated
02/19/15
20150050747

Directed dna co-polymer mass amplification for ssdna detection


The disclosure generally relates to the use of a bio-barcode (bbc) method for capture and demonstrates hybridization co-polymerization amplification readout of the bbc as a method of rapid detection of single stranded dna output with an increased sensitivity for the initial target input to the bbc assay. The bbc assay reporter ssdna can be modified for rapid readout.
Board Of Trustees Of Michigan State University
02/19/15
20150050720

Device for detection of analytes in affinity bioassays


A device for detection of analytes in affinity bioassays comprising at least one transparent wall portion, at least one test recess adapted to receive at least one test strip and arranged such that said test strip is visible through the transparent wall portion, at least one cavity adapted to receive a container containing a fluid sample, said cavity being in fluid communication with said at least one test recess, and piercing means arranged in correspondence with said at least one cavity, such that upon insertion of a container in the cavity the container is pierced and at least a portion of the sample is released from the container and reaches the test recess. The invention further relates to the use of such a device for detection of analytes of a nucleic acid amplification reaction and to a detection kit comprising such a device and a test strip..
Vircell, S.l.
02/19/15
20150050695

Helicase dependent amplification of dna molecules using nucleotide analogs


This invention covers processes for the isothermal amplification of dna molecules having a preselected sequence. It is based on the unexpected discovery that primers having, at some positions, adenine substituted by 2-aminopurine or diaminopurine, guanine by inosine, thymine by 2-thiothymine, and cytosine by n4-ethylcytosine (“samrs nucleotides”) were accepted by enzymes used in the standard helicase-dependent amplification (hda).
02/19/15
20150050660

Stable compositions for nucleic acid amplification and sequencing


The present invention is directed to compositions comprising mixtures of reagents, including thermostable enzymes (e.g., thermostable dna polymerases), buffers, cofactors and other components, suitable for immediate use in nucleic acid amplification or sequencing techniques without dilution or addition of further components. The compositions contain no stablizing agents (e.g., glycerol or serum albumin) and unexpectedly maintain activity for extended periods of time upon storage at temperatures above freezing.
Life Technologies Corporation
02/19/15
20150050657

Targeted enrichment and amplification of nucleic acids on a support


Provided herein is a method of selecting target nucleic acids on a support. The method includes providing a plurality of beads each bead comprising one or more oligonucleotides, providing a support with a plurality of primers with a sequence complementary to at least a portion of the oligonucleotides on the beads, contacting the beads with the support wherein the oligonucleotides on the beads bind to the primers on the support, performing an extension reaction by extending the primers on the support to produce capture oligonucleotides, contacting the support comprising the capture oligonucleotides with the target nucleic acids, and extending the capture oligonucleotides bound to target nucleic acids to produce target extension products comprising a sequence complementary to at least a portion of the target nucleic acids.
Illumina Cambridge Limited
02/19/15
20150050654

Detection of nucleic acid amplification in a porous substrate


The present disclosure relates to characterization of biological samples by amplification detection in a porous substrate. By way of example, a porous substrate may include amplification reagents configured to provide a signal when released during amplification.
General Electric Company
02/19/15
20150050651

Nucleic acids for nucleic acid amplification


Nucleic acids sequences that can be used for nucleic acid amplification, for example quantitative nucleic acid amplification, are provided herein.. .
Becton, Dickinson And Company
02/19/15
20150049876

Hearing device and fitting hearing device


A hearing device and a method for fitting the hearing device are provided. The method for fitting a monaural hearing device involve obtaining audiograms of both ears, and adjusting an amplification gain based on the audiograms of both ears, in which the audiograms comprise an audiogram of a first ear for wearing the monaural hearing device and an audiogram of a second ear not wearing the monaural hearing device..
Samsung Electronics Co., Ltd.
02/19/15
20150049228

Imaging unit, imaging apparatus and computer-readable medium having stored thereon a control program


There is a demand for increasing the dynamic range of an imaging unit. Provided is an imaging unit comprising a pixel section that outputs a pixel signal corresponding to a reset potential after a reset and a signal potential after charge accumulation; an amplifying section that amplifies the pixel signal with a first amplification ratio or a second amplification ratio that is different from the first amplification ratio; and a control section that causes the amplifying section to amplify the pixel signal corresponding to a change from the reset potential to the signal potential with the first amplification ratio, and then causes the amplifying section to amplify the pixel signal corresponding to a change from the signal potential to the reset potential with the second amplification ratio..
Nikon Corporation
02/19/15
20150048472

Multi-pixel avalanche photodiode


Semiconductor avalanche photo transistors and methods of manufacturing the same, operable for internal amplification of a photo signal and for use in detection of weak light signals, gamma rays and nuclear particles. The multi-pixel avalanche photo transistor devices can comprise a semiconductor layer, a plurality of semiconductor areas (pixels) forming a p-n-junction with the semiconductor layer, a common conductive grid separated from the semiconductor layer by a dielectric layer and individual micro-resistors connected said semiconductor areas with the common conductive grid.
Zecotek Photonics Inc.
02/12/15
20150045684

Heart rate extraction using neural wavelet adaptive gain control and neural pattern processing


An improved heart rate monitor is provided that can detect and distinguish a heartbeat from an otherwise contaminated system with noise components potentially larger than the signal of interest. Embodiments of the inventive monitor have an amplification system that eliminates large noise components so as not to saturate the system during detection of a desired low amplitude signal.
02/12/15
20150045258

Cascaded addition of target specific universal adapters to nucleic acids


The present invention generally pertains to methods for the addition of one or more nucleic acid adaptors to a pcr product. The present invention generally relates to a method for the cascaded, highly specific addition of universal nucleic acid adapters to one or more target nucleic acids in a single pcr amplification reaction, as well as a kit encompassing the same..
Gnubio, Inc.
02/12/15
20150045249

Nucleic acid detection method


A method detects nucleic acid with high sensitivity even when the target nucleic acid is detected by sandwich hybridization using neither nucleic acid amplification nor a sensitization technique. The method includes sequentially or simultaneously bringing a target nucleic acid or fragmentation product thereof, a plurality of detection probes, and a capture probe immobilized on a support, into contact with each other to hybridize the capture probe with the target nucleic acid or fragmentation product thereof and to hybridize the target nucleic acid or fragmentation product thereof with the plurality of detection probes, thereby binding the plurality of detection probes to the support through the capture probe and the target nucleic acid or fragmentation product thereof; and then detecting the plurality of detection probes bound to the support..
Toray Industries, Inc.
02/12/15
20150044682

Multiplex amplification reaction determination of campylobacter jejuni penner/capsule type


The inventive method and associated reagents relate to a molecular approach to determining campylobacter jejuni capsule/penner types. The invention also relates to a method of identifying campylobacter jejuni types using primers in a multiplex pcr assay..
02/12/15
20150043762

Hearing device and low power operation thereof


A hearing device, an acoustic apparatus and a sound processing method thereof are provided. The method includes detecting audio signals, determining whether the audio signals include a voice signal of a user, and controlling amplification of the audio signals according to a result of the determination..
Samsung Electronics Co., Ltd.
02/12/15
20150043057

Optical amplifier arrangement


An optical amplifier which integrates a pre-amplifier and a power amplifier in a single rectangular active medium to enable amplification of low power ultra-short pulses to optimal power levels. A seed beam passes through the amplification medium along a first pre-amplification path making multiple traverses of the medium.
Rofin-sinar Uk Ltd.
02/12/15
20150042972

Amplification photoresist exposure in semiconductor chip manufacturing


An electrical field is applied through an extreme ultraviolet (euv) photoresist layer along a direction perpendicular to an interface between the euv photoresist layer and an underlying layer. Secondary electrons and thermal electrons are accelerated along the direction of the electrical field, and travel with directionality before interacting with the photoresist material for a chemical reaction.
International Business Machines Corporation
02/12/15
20150042405

Power detection circuit and rf signal amplification circuit having the same


The present invention relates to a power detection circuit and an rf signal amplification circuit having the same. According to an embodiment of the present invention, a power detection circuit including a coupling unit adjacent to an rf matching inductor to extract induced power; a rectification unit for rectifying the signal output from the coupling unit to output the rectified signal; a slope adjustment unit connected between an output terminal of the rectification unit and a ground and adjusting a voltage slope for power detection by changing the output signal of the output terminal of the rectification unit according to changes in internal impedance; and a smoothing unit for receiving the output signal of the output terminal of the rectification unit to smooth the received signal into a dc voltage for power detection using the voltage slope is provided.
Samsung Electro-mechanics Co., Ltd.
02/05/15
20150038375

Methods and compositions for multiplex pcr


The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex pcr of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences.
Life Technologies Corporation
02/05/15
20150038360

Method for multiplex-detecting chronic myelogenous leukemia gene using cleavable probe


One embodiment of the present invention provides a detection kit for detecting a chronic myelogenous leukemia (cml) gene expression, wherein the detection kit includes a primer set which is specifically bound to the cml gene; and a cleavable probe which is specifically bound to the inside of a cml gene amplification product which is amplified by the primer set. Another embodiment of the present invention provides a method of measuring the cml gene expression by using the detection kit according to one embodiment of the present invention.
Samsung Life Public Welfare Foundation
02/05/15
20150038356

Genetic assays


Provided herein are methods, compositions, systems, and kits for recombination assays, many of which involve amplification reactions such as pcr or droplet digital pcr.. .
Bio-rad Laboratories, Inc.
02/05/15
20150038343

Methods and compositions for multiplex pcr


The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex pcr of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences.
Life Technologies Corporation
02/05/15
20150038342

Methods and compositions for multiplex pcr


The present invention provides methods, compositions, kits, systems and apparatus that are useful for multiplex pcr of one or more nucleic acids present in a sample. In particular, various target-specific primers are provided that allow for the selective amplification of one or more target sequences.
Life Technologies Corporation
02/05/15
20150038341

Digital amplification


The identification of pre-defined mutations expected to be present in a minor fraction of a cell population is important for a variety of basic research and clinical applications. The exponential, analog nature of the polymerase chain reaction is transformed into a linear, digital signal suitable for this purpose.
The Johns Hopkins University
02/05/15
20150037803

Apparatus and automatically analyzing biological samples


Provided are an apparatus and a method for automatically analyzing biological samples capable of performing the entire processes of dissolving the biological samples in protease and cell lysate to dissolve a nucleic acid in a solution, attaching the nucleic acid to magnetic particles, finally washing the magnetic particle to which the nucleic acid is attached with an organic solvent, drying the magnetic particles using a vacuum pump, eluting the target nucleic acid attached to the magnetic particles in an aqueous solution, adding and mixing the eluted target nucleic acid into a vessel containing a nucleic acid amplification reagent, real-time detecting amplification by irradiating excitation light to a reactor simultaneously with regulating a temperature to perform amplification to measure fluorescence, inactivating an amplified product using an ultraviolet lamp after amplification, obtaining an image through electrophoresis, and analyzing a molecular weight in a single apparatus.. .
Bioneer Corporation
02/05/15
20150037791

Methods and kits for multiplex amplification of short tandem repeat loci


Compositions, methods and kits are disclosed for use in simultaneously amplifying at least 20 specific str loci of genomic nucleic acid in a single multiplex reaction, as are methods and materials for use in the analysis of the products of such reactions. Included in the present invention are materials and methods for the simultaneous amplification of 23 and 24 specific loci in a single multiplex reaction, comprising the 13 codis loci, the amelogenin locus, an indel and at least six to ten additional str loci, including methods, kits and materials for the analysis of these loci..
Life Technologies Corporation
02/05/15
20150036824

Transmitter, receiver, quantum key distribution (qkd) system and quantum key distribution method


According to an embodiment, a transmitter transmits first transmission key data and second transmission key data as quantum information. The transmitter includes a first privacy amplifier and a second privacy amplifier.
Kabushiki Kaisha Toshiba
02/05/15
20150036703

Single mode propagation in fibers and rods with large leakage channels


Various embodiments include large cores fibers that can propagate few modes or a single mode while introducing loss to higher order modes. Some of these fibers are holey fibers that comprise cladding features such as air-holes.
Imra America, Inc.
02/05/15
20150036210

Optical amplifier device


The phase sensitive amplifier according to the present invention is a phase sensitive amplifier that uses the optical mixing using a nonlinear optical effect to amplify the signal light. The phase sensitive amplifier according to the present invention includes: the first second-order nonlinear optical element; and the second second-order nonlinear optical element.
02/05/15
20150035606

Time and amplitude alignment in envelope tracking amplification stage


The invention relates to a method of calibrating an envelope path and an input path of an amplification stage including an envelope tracking power supply, the method comprising: generating input signals having a known relationship for each of the input and envelope paths; and varying an amplitude and a delay of the signal in one of the envelope and input paths in order to reduce the variation in the power detected in a signal at the output of the amplification stage.. .
Nujira Limited
02/05/15
20150035598

Common-mode feedback differential amplifier


The present invention discloses a common-mode feedback differential amplifier circuit, a common-mode feedback differential amplification method, and an integrated circuit. In an example, a common-mode feedback (cmfb) loop conducts voltage division on a first common-mode signal to generate a second common-mode signal and a third common-mode signal, a differential amplifier sets a voltage of the signal with the higher voltage between the second common-mode signal and the third common-mode signal equal to a voltage of a first input terminal or a second input terminal, and the cmfb loop controls the differential amplifier to output an output signal with the minimum voltage equal to the voltage of the first common-mode signal..
Fairchild Semiconductor Corporation
02/05/15
20150035596

Versatile audio power amplifier


An audio power amplifier includes a first and a second amplification unit, each including a switching voltage amplifier, an output filter, a current compensator, an inner current feedback loop feeding a measurement of current measured at the output inductor back to a summing input of the current compensator, a voltage compensator coupled to the summing input of the current compensator, and an outer voltage feedback loop. A controlled signal path provides the output of the voltage compensator of the first amplification unit to the current compensator of the second amplification unit.
Bose Corporation
02/05/15
20150035013

Image pickup device


An image pickup device according to the present invention is an image pickup device in which a plurality of pixel are arranged in a semiconductor substrate. Each of the plurality of pixels includes a photoelectric conversion element, a floating diffusion (fd) region, a transfer gate that transfers charges in the first semiconductor region to the fd region, and an amplification transistor whose gate is electrically connected to the fd region.
Canon Kabushiki Kaisha
01/29/15
20150031575

Uses of ided nanostructures in nucleic acid technology


The present invention relates to compositions comprising a porous nanostructure of a known characteristics and a fragment of nucleic acid having a known sequence. Methods of use of the compositions were also provided, for example in dna amplification, detection, and dna sequencing..
Nvigen, Inc.
01/29/15
20150031559

Increased confidence of allele calls with molecular counting


Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (dbr) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment).
Population Genetics Technologies Ltd
01/29/15
20150031557

Detection of shiga toxin genes in bacteria


The disclosed invention is related to methods, compositions and kits for targeting nucleic acid derived from shiga toxin-producing bacteria such as e. Coli.
Gen-probe Prodesse, Inc.
01/29/15
20150031555

Method for correction of bias in multiplexed amplification


This invention relates a method to correct for bias inherent to multiplexed sequence amplification. The resulting corrected data is a much more accurate representation of true quantities than unprocessed data..
Gigagen, Inc.
01/29/15
20150031320

Adaptive harmonic rejection receiving device and method


The invention provides an adaptive harmonic rejection (hr) receiving device, including a low noise amplification module; at least one hr mixer; at least one non-harmonic rejection (nhr) frequency mixer; and a control device. A received signal passes through the low noise amplification, and then passes through the at least one hr mixer or the at least one nhr mixer; the control device measures a receiving signal strength index (rssi) after the received signal passes through the at least one hr mixer or the nhr mixer, and selects an nhr mixer or an appropriate hr mixer for the received signal according to a result of the measurement.
Montage Technology (shanghai) Co., Ltd.
01/29/15
20150031318

Transmitter and method with rf power amplifier having predistorted bias


A transmitter (32) generates a time-varying stabilized bias signal (82) from which sub-rf distortion signals (26, 29) have been cancelled. The distortion signals (26, 29) are byproducts of imperfect amplification and of biasing networks.
Crestcom, Inc.
01/29/15
20150031107

Pcr reaction mixtures with decreased non-specific activity


The present invention provides methods for improving the specificity of nucleic acid amplification comprising incubating a nucleic acid molecule with a polymerase-sso7 dna binding domain conjugate and arginine, spermidine, or spermine. The present invention also provides reaction mixtures and kits for improving the specificity of nucleic acid amplification..
Bio-rad Laboratories, Inc.
01/29/15
20150031087

Nucleic acid amplification method


The invention provides an ultra-rapid nucleic acid amplification method performed in a flow channel. Specifically, the invention provides a nucleic acid amplification method for performing a pcr reaction by supplying a pcr sample solution to a nucleic acid amplification device comprising a serpentine channel adapted to perform at least one pcr cycle, the nucleic acid amplification device comprising a dna denaturation temperature zone corresponding to the curved portions at one side, an annealing temperature zone corresponding to the curved portions at the other side, and an extension temperature zone positioned between the annealing and dna denaturation temperature zones, wherein the pcr sample solution is introduced in the form of sample plugs separated by gas into the serpentine channel using a pump, the sample solution being supplied into the channel in a state such that the solution is separated by gas into a segment corresponding to one pcr cycle or smaller segments..
National Institute Of Advanced Industrial Science And Technology
01/29/15
20150031086

Ligase-assisted nucleic acid circularization and amplification


Provided herein are methods for generation and amplification of a single-stranded dna circle in a single reaction vessel from a linear dna without any intervening purification steps. The single-stranded dna circle is generated via a template-independent single-stranded dna ligation.
General Electric Company
01/29/15
20150031039

Methods and device to balance radiation transference


A method and device for adjusting the temperature of a sample by heating a substrate with a laser diode light; said light projected on to the substrate to absorb the light and convert the light energy to a heat energy thereby raising the temperature of the substrate corresponding to the intensity of the light energy, the substrate configured to transfer the thermal energy substantially homogenously to the sample. The device or method suitable for amplification of a nucleic acid sample..
Agency For Science, Technology And Research
01/29/15
20150031038

Sample preparation methods


The present invention provides whole blood nucleic acid extraction methods, compositions, and kits, as well as nested isothermal amplification methods, compositions, and kits. In certain embodiments, these methods are applied to detecting lyme disease, including in patients without classic erythema migrans skin lesions..
Ibis Biosciences, Inc.
01/29/15
20150031036

Nucleic acid amplification reaction apparatus and nucleic acid amplifying method


A nucleic acid amplification reaction apparatus includes (a) a rotating body mounted with a nucleic acid amplification reaction container including reaction liquid in which nucleic acid is eluted and oil phase-separated from the reaction liquid, (b) a control section for rotating the rotating body and moving the reaction liquid back and forth between a first region and a second region, and (c) a fluorescence measuring device for performing fluorescence measurement of the reaction liquid in a position along a rotation track of the nucleic acid amplification reaction container at the time when the rotating body rotates.. .
Seiko Epson Corporation
01/29/15
20150031035

Method and device for collection and amplification of circulating nucleic acids


Provided herein are methods for the collection and amplification of circulating nucleic acids from a non-cellular fraction of a biological sample. Circulating nucleic acids are extracted from the non-cellular fraction and are circularized to generate single-stranded nucleic acid circles, which are then subsequently amplified by rolling circular amplification using random primers to produce an amplified library.
General Electric Company
01/29/15
20150031023

Method of detecting nucleic acids containing a genetic variation


Provided are a composition or a kit for detecting a nucleic acid with genetic variation including a first amplification blocking nucleic acid and a second amplification blocking nucleic acid, and a method of detecting a nucleic acid with genetic variation by using the same. Based on the above, a nucleic acid with genetic variation can be detected with high sensitivity and accuracy..
Samsung Electronics Co., Ltd.
01/29/15
20150031015

Identification of poliovirus strains


The present invention relates to methods for identifying and/or distinguishing polioviral strains, in particular polioviral strains used in vaccine production. The methods are based on selective hybridisation with oligonucleotides, i.e.
En Sport


Popular terms: [SEARCH]

Amplification topics: Amplification, Nucleic Acid, Nucleotide, High Resolution, Modulation, Feedback Signal, Nanoparticle, Semiconductor, Raman Amplifier, Resonance Frequency, User Interface, Transmitter, Methylation, Sample Preparation, Sequencing

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