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Amplification patents

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Xeno transduction system

Mixed reality augmentation

Date/App# patent app List of recent Amplification-related patents
 Polymeric carriers for immunohistochemistry and in situ hybridization patent thumbnailnew patent Polymeric carriers for immunohistochemistry and in situ hybridization
Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers having plural reactive functional groups that react with plural molecules of interest. Reactive functional groups, such as hydrazides, may be derivatized with a variety of detectable labels, particularly haptens.
 Method for detecting protein that interacts with target substance patent thumbnailnew patent Method for detecting protein that interacts with target substance
The present invention provides a method for detecting an interaction, which method can solve not only the problem of false negatives but also the problem of false positives. This method is a method for detecting a protein(s) that interact(s) with a target substance(s), the method comprising repeating a (1) transcription step, (2) assignment step, (3) selection step, and (4) amplification step, wherein: (a) in each of a plurality of times of preparation of a cdna library among the initial preparation of a cdna library and the round(s) of preparation of a cdna library in the later amplification step(s), the cdna library is prepared using a primer(s) having a sequence(s) specific to the time of preparation; (b) the cdna libraries prepared using the primers having sequences specific to the times of preparation are mixed, and sequences in the cdna library mixture are determined; (c) the determined sequences are subjected to measurement of the number(s) of molecules encoding the same candidate protein(s) for each time of preparation based on the sequence(s) specific to the time of preparation; and (d) a candidate protein(s) encoded by a molecule(s) that significantly increase(s) as the preparation rounds proceed is/are detected as the protein(s) that interact(s) with the target substance(s)..
 Allele-specific amplification patent thumbnailnew patent Allele-specific amplification
The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having a 3′-terminal nucleotide complementary to only one variant of the target sequence and having at least one nucleotide with a base covalently modified at the exocyclic amino group, wherein the allele-specific oligonucleotide is extended by a nucleotide-incorporating biocatalyst predominantly when hybridized to the variant of the target sequence for which it has said complementary 3′-terminal nucleotide.. .
 Chimeric primers with hairpin conformations and methods of using same patent thumbnailnew patent Chimeric primers with hairpin conformations and methods of using same
Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed. In one embodiment, a nucleic acid molecule having a target-specific primer sequence; an anti-tag sequence 5′ of the target-specific primer sequence; a tag sequence 5′ of the anti-tag sequence; and a blocker between the anti-tag sequence and the tag sequence is disclosed.
 Compositions and methods for genetic analysis of embryos patent thumbnailnew patent Compositions and methods for genetic analysis of embryos
The present disclosure provides for compositions and methods for genetic analysis of embryos. Generally, the compositions and methods provide for the acquisition of an sample containing rna from an embryo, genetic analysis involving various techniques such as sequencing-, hybridization- or amplification-based methods, and the detection of genetic alterations that may affect the health and quality of the embryo.
 Chromatography method, chromatography kit, and method of producing an insoluble carrier for chromatography patent thumbnailnew patent Chromatography method, chromatography kit, and method of producing an insoluble carrier for chromatography
A chromatography method including a step of developing a complex of a specimen and a labeled substance modified by a first bondable substance which can be bonded to the specimen on an insoluble carrier, a step of capturing the complex of the specimen and the labeled substance at a reactive site on the insoluble carrier, a step of washing the reactive site on the insoluble carrier using a washing liquid, a step of detecting the specimen which is captured at the reactive site after a signal of the labeled substance is amplified by an amplification liquid, in which the reactive site on the insoluble carrier includes (i) a second bondable substance which can be bonded to the specimen or a substance having affinity to the first bondable substance which can be bonded to the specimen, and (ii) polyethylene glycol having the molecular weight from 1,500 to 10,000.. .
 Short-pulsed compact mopa patent thumbnailnew patent Short-pulsed compact mopa
A master oscillator power amplifier (mopa) system includes an oscillator having a neodymium-doped gadolinium vanadate gain-medium and delivering seed-pulses. A length of single mode fiber is used to broaden the spectrum of the seed pulse.
 System for cooling devices patent thumbnailnew patent System for cooling devices
A cooling system is provided. The cooling system includes an enclosure.
 Multi-core amplification optical fiber and multi-core optical fiber amplifier patent thumbnailnew patent Multi-core amplification optical fiber and multi-core optical fiber amplifier
A multi-core amplification optical fiber includes a plurality of rare-earth-doped core portions and a cladding portion positioned at an outer periphery of the core portions and having refractive index lower than those of the core portions. When a doping concentration of the rare-earth of each of the core portions is 250 ppm to 2000 ppm, a relative refractive index difference of each of the core portions relative to the cladding portion is 0.5% to 2% at a wavelength of 1550 nm, and a core diameter of each of the core portions is 1 μm to 5 μm, a separation distance between each of the core portions and adjacent one of the core portions is set at equal to or larger than 30 μm and at equal to or smaller than 60 μm so that a light-crosstalk between the adjacent core portions is equal to or lower than −30 db..
 Optical amplification component and fiber laser device patent thumbnailnew patent Optical amplification component and fiber laser device
An optical amplification component 1 includes a heat dissipation plate 10 and an amplification optical fiber 20 arranged on the heat dissipation plate 10. A first fiber portion 20a extending from a reference position rp between a first end e1 and a second end e2 of the amplification optical fiber 20 toward the first end e1 and a second fiber portion 20b extending from the reference position rp toward the second end e2 are wound in a spiral around the reference position rp so as to be along each other as well as not to overlap with each other, and the distance between the first fiber portion 20a and the second fiber portion 20b increases toward the ends thereof..
new patent Mixed reality augmentation
Embodiments that relate to providing motion amplification to a virtual environment are disclosed. For example, in one disclosed embodiment a mixed reality augmentation program receives from a head-mounted display device motion data that corresponds to motion of a user in a physical environment.
new patent System and method for the detection and control of illicit trafficking of special nuclear materials
It is a system and method for the monitoring of the illicit traffic of fissile materials that can be used for the construction of nuclear bombs or not fissile that can be used for the construction of radiological dispersion devices; characterized by reducing the rate of spurious detection and increase the probability of detection compared with equivalent devices of the prior art. Some of its embodiments include the use of a radiation detector/telemeter ensemble with manual or automatic pointing and an ensemble of radiation detector/camera with an automatic object tracker along with data acquisition and processing electronics; which allow the calculation of the correlation between the characteristic profile produced by the mo and a predicted reference profile.
new patent Alarm detector
An alarm sounder and at least one sound amplification component having at least one horn shaped channel form an alarm detector. The at least one horn shaped channel has a throat end and an outlet end, the throat end being disposed corresponding to a sound-making end of the alarm sounder.
new patent Operational amplifier circuit
Provided is an operational amplifier circuit capable of operating with lower current consumption. An amplifier stage, a fir filter, and a sample and hold circuit are connected in series, thus enabling reduction of an input offset voltage and amplification of an input signal voltage without using an integral circuit.
new patent Xeno transduction system
An oscillation frequency power amplification circuit is disclosed herein having improved power and frequency receiver characteristics. The power circuit is characterized by having atmospheric capacitance of device electronic amplify resonate by antenna vessel.
Methods and systems for visualizing and evaluating data
A computer-implemented method of generating a digital polymerase chain reaction (dpcr) result is provided. The method includes detecting a first set of emission data from a plurality of samples, each included in a sample region of a plurality of sample regions, at a first time during an amplification period.
Sequence amplification with loopable primers
The present disclosure relates to the amplification of target nucleic acid sequences. This can be accomplished via the use of various primers.
Methods and devices for amplification of nucleic acid
The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array..
Multiplex nucleic acid detection methods
Methods for multiplex ligation-dependent probe amplification include (a) providing a sample tissue to query different target nucleic acids, (b) providing different probe sets for each of the target nucleic acids, each probe set including a first locus specific probe having a first adapter sequence and a first target specific portion and a second locus specific probe having a second adapter sequence, and a second target specific portion adjacent to the first target specific portion, (c) hybridizing the probe sets to the target sequences to form hybridization complexes, (d) ligating the hybridization complexes to form ligated probes, (e) amplifying the ligated probes to form amplicons, the amplifying step being carried out with a first universal primer including a region complementary to the first adapter sequence and a second universal primer including a region complementary to the second adapter sequence, and (f) detecting the amplicons in a detection system by sequencing each of the amplicons.. .
Detection and quantification of biomolecules using mass spectrometry
The present invention is directed in part to a method for detecting a target nucleic acid using detector oligonucleotides detectable by mass spectrometry. This method takes advantage of the 5′ to 3′ nuclease activity of a nucleic acid polymerase to cleave annealed oligonucleotide probes from hybridized duplexes and releases labels for detection by mass spectrometry.
Quantitative nuclease protection assay (qnpa) and sequencing (qnps) improvements
The present disclosure provides an improvement to quantitative nuclease protection assay (qnpa) and quantitative nuclease protection sequencing (qnps) methods. The disclosed methods use nuclease protection probes (npps) that include 5′-end and/or 3-end flanking sequences, which provide a universal hybridization and/or amplification sequence.
Methods for nucleic acid manipulation
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor.
Dna fragment detection method, dna fragment detection kit and the use thereof
The disclosure claims a cleaved deoxyribonucleic acid (dna) detection method, a dna fragment detection kit and use thereof. Wherein, the method includes the steps of: designing primers according to a test site or a test region of the dna fragment; cyclizing the dna fragment to obtain acyclized dna; implementing polymerase chain reaction (pcr) amplification for the cyclized dna by using the primers; and detecting the pcr amplification product.
Recombinase polymerase amplification
This disclosure describes related novel methods for recombinase-polymerase amplification (rpa) of a target dna that exploit the properties of recombinase and related proteins, to invade double-stranded dna with single stranded homologous dna permitting sequence specific priming of dna polymerase reactions. The disclosed methods have the advantage of not requiring thermocycling or thermophilic enzymes.
Organism identification panel
Methods and containers are provided for identifying a species, illustratively a bacterial species. Illustrative methods comprise amplifying various genes in the nucleic acid from the bacterial species in a single reaction mixture using pairs of outer first-stage primers designed to hybridize to generally conserved regions of the respective genes to generate a plurality of first-stage amplicons, dividing the reaction mixture into a plurality of second-stage reactions, each using a unique pair of second-stage primers, each pair of second-stage primers specific for a target bacterial species or subset of bacterial species, detecting which of the second-stage reactions amplified, and identifying the bacterial species based on second-stage amplification.
Method for quantifying human dna
The invention provides for a method for quantifying one or more nucleic acids of a genome in a sample comprising the steps of (a) amplifying a first nucleic acid to be quantified, (b) determining the amount of said first nucleic acid by comparison of the amount of amplification product from said first nucleic acid with at least one amplification product from a second template nucleic acid, (c) wherein said second template nucleic acid was generated using whole genome amplification and wherein the starting concentration of the second template nucleic acid is known.. .
Direct amplification and detection of viral and bacterial pathogens
Provided are methods for identifying the presence or absence of a target nucleic acid from a microorganism using direct amplification without a step of extraction of the nucleic acids, but retaining substantially the same specificity and sensitivity of methods assaying extracted nucleic acids. Further provided are reagent mixtures that allow for direct amplification of a sample, without the step of nucleic acid extraction..
Radiographic imaging control device, radiographic imaging system, radiographic imaging device control method, and recording medium
A radiographic imaging control device is provided with a radiation detector, amplifiers and a controller. A plurality of pixels are arrayed in the radiation detector, each pixel including a sensor portion that generates charges in accordance with irradiated radiation and a switching element that is for reading out the charges generated at the sensor portion.
Method and equipment for controlling radio-frequency signal
The present invention describes a rf signal control method and device that adjusts the first down-converter gain attenuation and uses the adjusted first down-converter gain attenuation to change the rf signal. The rf signal control method and device also uses a determined linear filter parameter to perform linearity improvement on the digital signal after the rf signal goes through a down-converter and analog-to-digital converter.
Control method and equipment for radio-frequency signal
The present invention describes a rf signal control method and device that changes the gain attenuation in real time and uses the changed gain attenuation to adjust the rf input signal. The rf signal control method and device also uses determined linear filter parameters for linearity improvement on the digital signal that results from a down-conversion and analog-to-digital converter on the rf input signal.
Circuit arrangement for compensating an attenuation occurring in an antenna signal connection between a mobile terminal and an antenna and compensation method for this purpose
A circuit arrangement (1) is described for compensating an attenuation (ko, ka, ka1, ka2) occurring in an antenna signal connection (2) between a mobile terminal (3) and an antenna (4) with at least one antenna signal amplifier (5a, 5b) in the antenna signal connection (2) and with a control unit (8) for setting an amplification factor (v) by which the antenna signal routed through an allocated antenna signal amplifier (5a, 5b) is amplified or attenuated. The circuit arrangement (1) has a detection unit (7) for detecting an antenna signal power (p) of the antenna signal in the signal path of the antenna signal connection (2).
Method and apparatus for random access channel probe initialization using transmit diversity
Embodiments of the present invention may separately utilize transmit paths of a mobile transmit diversity device to initialize communication with a base station over a random access channel, particularly where the transmit paths have power amplifiers with different characteristics, e.g., different power amplification.. .
Defect inspecting apparatus and defect inspecting method
An invention being applied is a defect detecting apparatus that has: an illuminating optical system with a laser light source for irradiating a sample on whose surface a pattern is formed with light; a detecting optical system with a sensor for detecting light generated from the sample illuminated by the illuminating optical system; and a signal processing unit that extracts a defect from an image based on the light detected by the detecting optical system, in which an amplification rate of the sensor is dynamically changed during a time when the light is detected by the detecting optical system.. .
Vehicle camera image quality improvement in poor visibility conditions by contrast amplification
A vision system for a vehicle includes an imaging sensor disposed at the vehicle and having an exterior field of view, and an image processor. The imaging sensor captures image data and the image processor is operable to process successive frames of captured image data.
Receiver circuit, phased-array receiver and radar system
A receiver circuit, comprises an input balun circuit comprising a balanced balun output and being capable of receiving rf signals, an input amplification circuit comprising a balanced amplifier input and a balanced amplifier output, a single balanced in-phase mixing circuit comprising a first unbalanced rf mixer input and a balanced in-phase mixing frequency input, and a single balanced quadrature mixing circuit comprising a second unbalanced rf mixer input and a balanced quadrature mixing frequency input. The balanced amplifier input is connected to the balanced balun output, a first terminal of the balanced amplifier output is connected to provide an amplified rf signal to the first unbalanced rf mixer input and a second terminal of the balanced amplifier output is connected to provide a phase-shifted amplified rf signal to the second unbalanced rf mixer input..
High efficiency amplification
A radio frequency amplification stage comprising: an amplifier for receiving an input signal to be amplified and a power supply voltage; and a power supply voltage stage for supplying said power supply voltage, comprising: means for providing a reference signal representing the envelope of the input signal; means for selecting one of a plurality of supply voltage levels in dependence on the reference signal; and means for generating an adjusted selected power supply voltage, comprising an ac amplifier for amplifying a difference between the reference signal and one of the selected supply voltage level or the adjusted selected supply voltage level, and a summer for summing the amplified difference with the selected supply voltage to thereby generate the adjusted supply voltage.. .
High-frequency amplifier module and high-frequency amplifier module unit
A high-frequency amplifier module includes a driver-stage amplifier 3 that amplifies an rf signal input thereto from an rf input terminal 1, and a final-stage amplifier 5 that amplifies the signal amplified by the driver-stage amplifier 3 and outputs the signal after the amplification to an rf output terminal 7. The driver-stage amplifier 3 is fabricated on a silicon substrate 11, while the final-stage amplifier 5 is fabricated on a gallium arsenide substrate.
Two-dimensional detection system for neutron radiation in the filed of neutron scattering spectrometry
This invention relates to a two-dimensional detection system for neutron radiation comprising a means (1) for emitting a neutron beam (10), a support means (2) adapted for receiving a sample (3), a photoemission means (5) adapted for being activated by a neutron radiation, a cooled low light level charge-coupled detection device (7). The emission means (1) emits a monochromatic neutron beam (10).
Method and device for detecting elementary particles
Provision is made in a method and a device for detecting elementary particles such as for example protons, ions, electrons, neutrons, photons or the like in a detector, wherein a charge pulse is generated in the detector when a particle passes through the detector and every charge pulse is subsequently converted into an electric signal and the signal is indicated and/or recorded in particular after amplification, for individual signals to be amplified in a first, fast amplifier and/or in each case a plurality of signals to be integrated in a second, slow amplifier, as a result of which it becomes possible for individual particles to be detected and in particular at increased signal or count rates for an integration thereof to be provided.. .
Drilling system having a super-capacitor amplifier and a method for transmitting signals
A method and a drilling system that may include a drilling element for drilling a hole in a geological formation; a sensor module arranged to collect information about the drilling; a transmitter that is arranged to receive the information from the sensor module, amplify the information by a super-capacitor amplifier to provide amplified information and to provide the amplified information to a first element and to a second element of an antenna, the first and second elements of the antenna are located at two opposite sides of a band gap; wherein the antenna is arranged to transmit the amplified information via the geological formation; wherein the super-capacitor amplifier comprises a plurality of switched capacitor converters, each switched capacitor converter comprises a plurality of converter stages, each converter stage comprises capacitors and switches that are arranged to perform a current amplification of an input signal; wherein each converter stage is arranged to operate with alternating charge cycles and discharge cycles.. .
Enhancing performance of spectral band replication and related high frequency reconstruction coding
The present proposes new methods and an apparatus for enhancement of source coding systems utilising high frequency reconstruction (hfr). It addresses the problem of insufficient noise contents in a reconstructed highband, by adaptive noise-floor addition.
Liquid ejection device and liquid ejection surgical instrument
A liquid ejection device includes a drive waveform generator generating a drive waveform signal; a modulator performing pulse modulation on a signal from the drive waveform generator to provide a modulated signal; a digital power amplifier performing power amplification on the modulated signal to provide an amplified digital signal; a lowpass filter smoothing the amplified digital signal to provide a drive signal of an actuator; a compensator advancing the phase of the drive signal to provide a negative feedback signal; and a subtractor providing a differential signal between the drive waveform signal and the negative feedback signal as an input signal to the modulator. The liquid ejection device can be used as a liquid ejection surgical instrument..
Method and kit for constructing plasma dna sequencing library
The disclosure relates a method and a kit for constructing a plasma deoxyribonucleic acid (dna) sequencing library. The method provided by the disclosure includes: extracting a plasma dna; making the plasma dna ligate to a sequencing linker, and purifying a ligation product; performing polymerase chain reaction (pcr) amplification for the purified ligation product, purifying the pcr amplification product, and obtaining the plasma dna sequencing library, wherein, the method does not include the step of performing 5′-terminus phosphorylation for the plasma dna.
Methods of nucleic acid amplification and sequencing
Methods for amplification and sequencing of at least one nucleic acid comprising the following steps: (1) forming at least one nucleic acid template comprising the nucleic acid(s) to be amplified or sequenced, wherein said nucleic acid(s) contains at the 5′ end an oligonucleotide sequence y and at the 3′ end an oligonucleotide sequence z and, in addition, the nucleic acid(s) carry at the 5′ end a means for attaching the nucleic acid(s) to a solid support; (2) mixing said nucleic acid template(s) with one or more colony primers x, which can hybridize to the oligonucleotide sequence z and carries at the 5′ end a means for attaching the colony primers to a solid support, in the presence of a solid support so that the 5′ ends of both the nucleic acid template and the colony primers bind to the solid support; (3) performing one or more nucleic acid amplification reactions on the bound template(s), so that nucleic acid colonies are generated and optionally, performing at least one step of sequence determination of one or more of the nucleic acid colonies generated. Solid supports, kits and apparatus for use in these methods..
Method for the spatial arrangement of sample fragments for amplification and immobilization for further derivatizations
The invention relates to a method for performing a biochemical or chemical reaction for an isolated, spatially separated amplification of sample fragments during a simultaneous immobilization and spatial arrangement of the sample fragments and reaction products, the amplification products, on one or more suitable solid phases for subsequent derivatizations.. .
High throughput paired-end sequencing of large-insert clone libraries
The present invention is related to genomic nucleotide sequencing. In particular, the invention describes a paired end sequencing method that improves the yield of long-distance genomic read pairs by constructing long-insert clone libraries (i.e., for example, a fosill library or a foscn library) and converting the long-insert clone library using inverse polymerase chain reaction amplification or shearing and recircularization of shortened fragments into a library of co-ligated clone-insert ends.
Methods of detecting low copy nucleic acids
Methods are provided for detecting low copy nucleic acids of interest in a sample. In one method, a sample comprising a nucleic acid of interest is aliquotted into a plurality of reaction mixtures, at least two of which are single-copy reaction mixtures.
Safe sequencing system
The identification of mutations that are present in a small fraction of dna templates is essential for progress in several areas of biomedical research. Though massively parallel sequencing instruments are in principle well-suited to this task, the error rates in such instruments are generally too high to allow confident identification of rare variants.
Methods for rapid identification and quantitation of nucleic acid variants
There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products..
Method for the detection of copy number variations
A method for the detection of copy number variations (cnvs) that combines similar sequences with melting curve analysis. The method consists of the following steps: 1) screening similar endogenous reference sequences or synthetic similar exogenous reference sequences in the entire genome according to the target sequence; 2) aligning the target sequence and the reference sequence and designing common amplification primers; 3) amplifying the target sequence and the reference sequence in a same reaction tube using a pair of common primers; and 4) analyzing the pcr product by melting curve analysis.
Detection of genetic or molecular aberrations associated with cancer
Systems, apparatus, and methods are provided for determining genetic or molecular aberrations in a biological sample from an organism. Biological samples including cell-free dna fragments are analyzed to identify imbalances in chromosomal regions, e.g., due to deletions and/or amplifications in a tumor.
Method and apparatus for predicting susceptibility to a developmental disorder
A nucleotide sequence signal amplification composition that includes an isolated, synthetic nucleotide sequence of greater than 7 nucleotides. The sequence is a fragment of seq id no:3 and further comprising a t nucleotide at position 1438 of seq id no:3 and one or more primers that bind to the synthetic nucleotide sequence, a thermostable dna polymerase, a restriction enzyme, or a combination thereof..
Compositions, methods and kits to detect adenovirus nucleic acids
The disclosed invention is related to methods, compositions, kits and isolated nucleic acid sequences for targeting adenovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers.
Rabies virus like particle production in plants
A method of producing a virus like particle (vlp) in a plant is provided. The method comprises introducing a first nucleic acid into the plant, or portion of the plant.
Communication system and method with papr and backoff configured for equilibrium
A communication system (20) includes a transmitter (22) having a peak controller (38) which controls papr to operate in accordance with a noise constraint. A backoff controller (60) operates in conjunction with an amplifier section (46) to cause the amplifier section (46) to maximize the amplification it applies while maintaining a predetermined degree of amplifier linearity.
Adapted piecewise linear processing device
A piecewise linear processing device applies different amplification rates according to a general environment and a low luminance environment where much noise exists. The piecewise linear processing device includes a knee point storing unit configured to store a user's default setting value and low luminance setting value; a luminance detecting unit configured to detect a noisy environment to output a current luminance information signal and a maximum luminance information signal; an adaptive knee point supply unit configured to receive the default setting value, the low luminance setting value, the current luminance information signal, and the maximum luminance information signal to supply a adjusted adaptive knee point according to a degree of noise; and a piecewise linear processing unit configured to apply a section amplification rate to an input data on the basis of a region corresponding to the adaptive knee point..
Extended variable gain amplification bandwidth with high-frequency boost
An apparatus having a circuit is disclosed. The circuit may be configured to (i) receive an input signal from a communication channel and (ii) generate an intermediate signal by amplifying the input signal (a) by a low-frequency gain in response to an amplitude control signal and (b) by a high-frequency gain in response to a boost control signal..
Sensor circuit
Provided is a sensor circuit which can amplify a sensor signal at high speed and with a high amplification factor without increasing the current consumption. The sensor circuit includes a primary amplifier for amplifying in advance a differential output signal which is a current signal of a sensor element, a secondary amplifier for amplifying the amplified differential output signal, a constant voltage generating circuit for maintaining a sensor element driving current to be constant, and a feedback circuit for feeding back a feedback signal to adjust an amplification factor.
Wearable apparatus to detect sleep stage information of an individual
A monitor device and associated methodology are disclosed which provide a self contained, relatively small and continuously wearable package for the monitoring of heart related parameters, including ecg. The detection of heart related parameters is predicated on the location of inequipotential signals located within regions of the human body conventionally defined as equivalent for the purpose of detection of heart related electrical activity, such as on single limbs.
Wearable apparatus to detect pulse transit time
A monitor device and associated methodology are disclosed which provide a self contained, relatively small and continuously wearable package for the monitoring of heart related parameters, including ecg. The detection of heart related parameters is predicated on the location of inequipotential signals located within regions of the human body conventionally defined as equivalent for the purpose of detection of heart related electrical activity, such as on single limbs.
Method for large-scale synthesis of long-chain nucleic acid molecule
Systems and methods for synthesizing long-chain nucleic acids molecules are disclosed. The systems and methods described in this application use a ligation- purification-amplification (“lpa”) technique.
Multiplexed digital assay with specific and generic reporters
Digital assay system, including methods, apparatus, and compositions, for performing target assays in partitions each containing a generic reporter and a specific reporter for target amplification.. .
Multiplexed digital assay with data exclusion for calculation of target levels
Digital assay system, including methods and apparatus, for calculating a level of one or more targets. In an exemplary method, data for amplification of a plurality of targets including a first target may be collected from partitions.
Methods and compositions for amplification and detection of micrornas
A method and system for amplifying non-coding rna, microrna, and small polynucleotide sequences through the generation of a pool of signature sequences to the target sequences. The target sequences can be amplified through dna synthesis, rna synthesis, or the combination of dna and rna synthesis.
Automated cancer diagnostic methods using fish
In various embodiments methods for automated screening for gene amplification in biological tissue samples using an automated fluorescence microscope to analyze fluorescence in situ hybridized samples are provided. Various additional embodiments provide methods of high throughput screening for gene amplification..
Sequence based genotyping based on oligonucleotide ligation assays
The invention relates to a method for the detection of a target nucleotide sequence in a sample based on an oligonucleotide ligation assay wherein probes are used that contain (a combination of) sequence-based identifiers that can identify the sample and the target sequence (i.e. Locus and/or allele combination) wherein after the ligation step, the ligated probes, or after amplification, the amplified ligated probes, are restricted using restriction enzymes to cut of part of the probes and continue with those parts (identifiers and target sequence) that contain the relevant information in the sequencing step..
Fast detection of collocated rf jammers facilitating optimized gain setting selection of front-end receiver amplifiers
In collocated radios, interference is mitigated to permit concurrent radio operation. In response to detection of imminent transmission of interfering wireless (i.e., rf jammer) signals, gain settings of one or more stages of front-end receiver amplifiers may be quickly configured to permit concurrent frequency division operation instead of consecutive time-division operation.

Popular terms: [SEARCH]

Amplification topics: Amplification, Nucleic Acid, Nucleotide, High Resolution, Modulation, Feedback Signal, Nanoparticle, Semiconductor, Raman Amplifier, Resonance Frequency, User Interface, Transmitter, Methylation, Sample Preparation, Sequencing

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