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Allergy

Allergy-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Novel high throughput assay for finding new jak3 interacting compounds, biomolecules, and inhibitors.
December 03, 2015 - N°20150344934

Janus kinase 3 is a non-receptor tyrosine kinase that mediates signals initiated by cytokines through interactions with the receptors of cytokines. Abnormal activation of jak3 was associated with human hematologic and epithelial malignancies. Inhibitors of jak3 have shown utility in many different disease such as autoimmune disorders, allograft rejection during transplantation, acute lymphoblastic leukemia, type 1 diabetes, rheumatoid arthritis and allergy and ...
Method of genetically altering and producing allergy free cats
December 03, 2015 - N°20150344908

A transgenic cat with a phenotype characterized by the substantial absence of the major cat allergen, fel d i. The phenotype is conferred in the transgenic cat by disrupting the coding sequence of the target gene with a specialized construct. The phenotype of the transgenic cat is transmissible to its offspring.
System and method for multiple allergen testing
December 03, 2015 - N°20150342514

The testing apparatus includes a capsule 108 tray and a hand held allergen applicator 104 that facilitates convenient storage and easy application of such allergens simultaneously. The hand held applicator 104 includes a plurality of prongs to administer the respective plurality allergen under the skin of the patient. The allergy testing apparatus provides for efficient pre-wetting of the prongs with respective allergens to ...
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Design of oligonucleotide analogs as therapeutic agents
November 19, 2015 - N°20150329864

It is believed that the compounds and compositions as described herein have therapeutic utility against a variety of diseases, including viral diseases, autoimmune diseases (such as, allergy, asthma, and inflammatory disorders) and cancer.
Igy composition for use in celiac disease
Charite - Universitatsmedizin Berlin
November 19, 2015 - N°20150329624

The present invention relates to an igy composition characterized in that said igy composition contains igy antibodies, fragments, and/or fab fragments thereof that specifically bind to a peptide with the amino acid sequence of seq id no: 1 and to the use of this igy composition in the therapy of celiac disease, rheumatism, and/or wheat allergy.
Novel immunotherapeutic molecules and uses thereof
Health, Alfred
November 19, 2015 - N°20150328294

The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with t lymphocytes in subjects having peanut allergy, or allergy to other tree nuts, and genetic sequences encoding same. These molecules are preferably immunointeractive with t cells in subjects having an allergy to the ara h 1 allergen. The molecules of the present invention are ...
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Process for producing an allergen extract
Laboratorios Leti, S.l.
October 29, 2015 - N°20150306211

The present invention discloses processes for producing native, depigmented and polymerised allergen extracts. The invention further discloses extracts produced via the processes, and pharmaceutical and vaccine compositions comprising the extracts, for diagnosis and treatment of allergy.
Methods of treating or preventing respiratory conditions
Mesoblast, Inc.
October 29, 2015 - N°20150306146

The present disclosure provides methods of treating or preventing respiratory condition and/or for treating an ige-mediated allergy and/or for reducing an allergic response to an allergen and/or for inducing anergy to an allergen in a subject and/or improving lung function in a subject suffering from an allergy comprising administering to a subject a population of cells ...
New fusion proteins for the treatment of allergic diseases
Veteriaerinstituttet
October 22, 2015 - N°20150299294

The present invention relates to a fusion protein comprising a first peptide and a second peptide linked together with a linker, wherein the first peptide is an allergen and the second peptide is a targeting unit and the targeting unit is a fgl-2 c-terminal peptide according to seq id no 1. Provided herein are also uses of said fusion protein as ...
Bifidobacterium for dust mite allergy
N.v. Nutricia
October 22, 2015 - N°20150297703

A composition comprising bifidobacterium breve for use in improving lung function in human subjects suffering from dust mite allergy.
Allergy treatment using acid treated aqueous whey protein extract
Women's And Children's Health Research Institute
October 22, 2015 - N°20150297641

The invention relates to manufacture of whey protein extracts, to infant formula and to reducing or preventing food allergy. The whey protein extract is produced from a whey protein-containing composition by contacting a whey protein-containing composition with an aqueous solution to form a sample including a soluble protein-containing component and an insoluble component; recovering the soluble protein-containing component from the ...
System and method for automatic reading of an allergy
Ergylink
October 22, 2015 - N°20150297129

A system and method for automatic reading skin for an allergy to a substance, includes a consumer electronics device that acquires images of skin; a consumable member having a surface divided into elementary areas, each elementary area with a different possible allergenic substance; and a palette that, when applied against each elementary area brings the depositing part into contact with ...
Allergy skin test applicator, and related testing tray, testing kit and testing method
October 15, 2015 - N°20150289794

An allergy testing kit contains a plurality of allergy testing applicators, an allergy testing tray and a plurality of allergen bottles each containing an allergen. Each of the applicators contains an elongated handle, a plurality of arms extending from the elongated handle and disposed in an asymmetrical configuration, and a plurality of legs with tines extending from each of the ...
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M cells and artificial skin sheet
October 01, 2015 - N°20150273115

[problem] to provide m cells having excellent strength and anti-allergy activity and an artificial skin sheet formed from the m cells. [solution] gp2 contained in the m cells is transferred to the intracellular tight junction and galectin 9 is expressed in the m cells. Moreover, a structure is formed in which both gp2 and galectin 9 are present at the m cell ...
Plastic blood lancet
September 24, 2015 - N°20150265198

The present invention provides a surgically invasive pointed article for skin penetration and capillary whole blood extraction whose penetration ability can be disabled after use by deforming the tips. The present invention is made by injection moulding a plastic needle 35 having an anchoring means 45 using a first material, followed by another injection moulding process to over-mould a first body segment 20 ...
Compositions for immunotherapy
Hal Allergy Holding B.v.
September 10, 2015 - N°20150250870

The present invention relates to compositions which can be used in immunotherapy and especially to compositions which can be used in immunotherapy for mammals suffering from a peanut allergy. The present invention further relates to the use of the present compositions for the treatment of a mammal suffering from an allergy by immunotherapy and the use of the present compositions ...
Nutritional compositions containing ceramide and uses thereof
Mead Johnson Nutrition Company
September 10, 2015 - N°20150250220

The present disclosure relates to nutritional compositions that include at least one ceramide. The nutritional compositions may further include galactose, sialic acid, or cholesterol. Ceramide and galactose may be provided by a plant-based source. The nutritional composition including ceramide and galactose from a plant base source may reduce the risk of cross-contaminating the nutritional composition with animal-based protein allergens. These ...
Benzimidazole derivatives as pi3 kinase inhibitors
Glaxosmithkline Llc
September 03, 2015 - N°20150246889

This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ oh kinase family (hereinafter pi3 kinases), suitably, pi3kα, pi3kδ, pi3kβ, and/or pi3kγ. Suitably, the present invention relates to the use of benzimidazoles in ...
Substituted fused tricyclic compounds, compositions, and medicinal applications thereof
August 27, 2015 - N°20150239886

The compounds of the present invention are useful in the treatment, prevention or suppression of diseases and disorders mediated by jak activity. Such conditions include, but not limited to, arthritis, alzheimer's disease, autoimmune thyroid disorders, cancer, diabetes, leukemia, t-cell prolymphocytic leukemia, lymphoma, myleoproliferation disorders, lupus, multiple myeloma, multiple sclerosis, osteoarthritis, sepsis, psoriatic arthritis, prostate cancer, t-cell autoimmune disease, inflammatory diseases, ...
Novel histamine releaser contained in human sweat
Hiroshima University
August 27, 2015 - N°20150238581

Provided arc a sweat allergy antigen, an antibody capable of binding to the antigen specifically, and others, which are produced utilizing a microorganism-originated protein that exists in sweat allergy patient in a dissolved state or a partial peptide of the protein.
Use of anti-cd1 antibodies for the modulation of immune responses
Beth Israel Deaconess Medical Center, Inc.
August 20, 2015 - N°20150231234

The invention provides methods for the administration of an anti-cd1 antibody for the treatment or prevention of a variety of disorders, such as autoimmune disease, viral infection, bacterial infection, parasitic infection, infection by a eukaryotic pathogen, allergy, asthma, inflammatory condition, graft versus host disease, graft rejection, immunodeficiency disease, spontaneous abortion, pregnancy, and cancer.
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