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This page is updated frequently with new Allergy-related patent applications.




Date/App# patent app List of recent Allergy-related patents
06/23/16
20160176849 
 N-cyanomethylamides as inhibitors of janus kinase patent thumbnailnew patent N-cyanomethylamides as inhibitors of janus kinase
The present invention relates to compounds of general formula (1) that are inhibitors of janus kinase (jak), a family of tyrosine kinases that are involved in inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons. In particular, the compound of the invention inhibits jak1 and/or jak2 and/or jak3 sub families.

06/16/16
20160169907 
 Method for prognosis of the efficacy of oral immunotherapy for the treatment of allergy to proteins in cow's milk patent thumbnailMethod for prognosis of the efficacy of oral immunotherapy for the treatment of allergy to proteins in cow's milk
The present invention relates to a method for prognosis of the efficacy of oral immunotherapy for the treatment of allergy to proteins in cow's milk providing a solution to the problems stated in the state of the art since it provides a method which allows making a prognosis of the number of reactions that will be produced during oral immunotherapy (oit) against proteins in cow's milk and/or an estimate of the treatment time required to achieve tolerance or desensitization during oit against proteins in cow's milk and/or the need for pre-medication during oit in a human subject.. .
Fundación Para La Investigación Biomédica Del Hospital Clinico San Carlos


06/16/16
20160168248 
 Regulatory t cell mediator proteins and uses thereof patent thumbnailRegulatory t cell mediator proteins and uses thereof
In particular methods of using these proteins and compounds, preferably antibodies, which bind or modulate (agonize or antagonize) the activity of these proteins, as immune modulators and for the treatment of cancer, autoimmune disease, allergy, infection and inflammatory conditions, e.g. Multiple sclerosis is disclosed.

06/16/16
20160166563 
 Anti-allergy benzocycloheptathiophene derivatives patent thumbnailAnti-allergy benzocycloheptathiophene derivatives
Or a pharmaceutically acceptable salt thereof, solvate, or prodrug thereof, and a pharmaceutically acceptable carrier, vehicle or excipient.. .

06/16/16
20160166439 
 Long-term effective patch structure patent thumbnailLong-term effective patch structure
A long-term effective patch structure includes a binding layer, an absorbing layer and a water-proof layer sequentially stacked together. The binding layer has a function of attaching and fixing, and is configured to be attached and fixed on a skin.
Sigknow Biomedical Corporation Ltd.


06/09/16
20160159927 
 Identification of vsig8 as the putative vista receptor (v-r) and use thereof to produce vista/vsig8 agonists and antagonists patent thumbnailIdentification of vsig8 as the putative vista receptor (v-r) and use thereof to produce vista/vsig8 agonists and antagonists
The receptor for vista is identified (vsig8) as well as the use of this receptor in the identification or synthesis of agonist or antagonist compounds, preferably antibodies, polypeptides and fusion proteins which agonize or antagonize the effects of vsig8 and/or vista and/or the vsig8/vista binding interaction. These antagonists may be used to suppress vista's suppressive effects on t cell immunity, and more particularly used in the treatment of cancer, or infectious disease.
Immunext, Inc.


06/09/16
20160159775 
 Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor patent thumbnailBenzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor
Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by h4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.. .
Janssen Pharmaceutica Nv


06/02/16
20160155347 
 Devices, systems and methods of assessing the foundations for the healthy development of an infant or a young child patent thumbnailDevices, systems and methods of assessing the foundations for the healthy development of an infant or a young child
Devices, systems and methods assess one or more of the risk of an allergy, immediate and/or later in life, for the infant or young child; the risk of an underdeveloped immune system, immediate and/or later in life, for the infant or young child, and/or the immediate risk of a not well-functioning digestive system for the infant or young child, preferably all of these. Optionally, the risk of obesity, immediate and/or later in life, can be additionally assessed.
Nestec S.a.


06/02/16
20160151481 
 Pharmaceutical product comprising mite allergen extract(s) and a  the manufacture thereof patent thumbnailPharmaceutical product comprising mite allergen extract(s) and a the manufacture thereof
The invention relates to a pharmaceutical product comprising an allergen extract or an allergoid thereof for the treatment and/or prevention of allergy and allergic asthma caused by house dust mites, which extract comprises at least one extract of mite bodies selected from the following groups a)-b): a) an extract of der p mite bodies, and b) an extract of der f mite bodies, and at least one extract of mite cultures selected from the following groups c)-g): c) an extract of der p faecal particles, d) an extract of der f faecal particles, e) an extract of der f whole mite culture, f) an extract of an der p whole mite culture, and g) a combination of extracts c) to f).. .
Alk-abelló A/s


06/02/16
20160151426 
 Preparation of bee venom with allergenic components removed patent thumbnailPreparation of bee venom with allergenic components removed
Disclosed is a method for manufacturing a separated and purified bee venom (separated pbv) not possessing allergy-triggering effects by reducing or eliminating allergy-inducing components contained in a bee venom via ultrafiltration, thereby producing a pvb with desirable pharmacological effects while fundamentally blocking allergies that may be induced by the same. The manufacturing method of the present invention includes a first step of preparing a purified bee venom powder; a second step of preparing a bee venom liquid by mixing the purified bee venom powder with distilled water; a third step of removing allergic ingredients contained in the bee venom liquid via ultrafiltration through a membrane having a cut-off size of 10 kda; and a fourth step of obtaining a separated pbv with the allergenic components removed; wherein the distilled water to be mixed with the purified bee venom powder in the second step is used in the range of from 1000 ml to 1500 ml per 1 g of the purified bee venom powder, the allergenic components removed through the ultrafiltration membrane in the third step are phospholipase a2 and hyaluronidase, and the separated pbv obtained in the fourth step contains 4 wt % or higher of apamin, and 50 wt % or higher of melittin..
Chung Jin Biotech Co., Ltd Hanyang Univ Ansan Campus, Sa-dong


05/26/16
20160145353 

Treatment of food intolerance and food allergy with iga


A process is provided for inhibiting symptoms of food allergy or food intolerance in a subject that includes the oral adminstration to the subject suffering from food allergy or food intolerance an igm. When administered in a therapeutic quantity based on the subject characteristics and the type of igm, symptoms of food allergy or food intolerance in that subject are inhibited.

05/26/16
20160145336 

Effector-deficient anti-cd32a antibodies


Effector-deficient anti-cd32a monoclonal antibodies are encompassed, as are method and uses for treating cd32a-mediated diseases and disorders, including, thrombocytopenia, allergy, hemostatic disorders, immune, inflammatory, and autoimmune disorders.. .
Adventist Health System/sunbelt Inc.


05/26/16
20160143464 

Breathable pillow


An integrated padded mesh material may be used in pillows or pillowcases for improved air flow around a user of the pillow or pillowcase during rest. When used in a pillow, the material may substantially cover the side of the pillow that a user's head rests upon.
Breathablebaby, Llc


05/19/16
20160138022 

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response


The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist.
Idera Pharmaceuticals, Inc.


05/12/16
20160130311 

T cell epitopes derived from alt a 1 or alt a 5 for the treatment of alternaria alternata allergy


The application discloses peptides capable of preventing or treating fungal disease, including fungal allergy disease.. .
Alergenetica Sl


05/12/16
20160128597 

Thin planar biological sensor


A thin planar biological sensor is provided, comprising at least one flexible electrode used for contacting a subject's skin and measuring biological signal. The flexible electrode is made of silicon-silver-based material, in which a ratio of silicon to silver-compound is about 7:3.
National Chiao Tung University


05/05/16
20160121116 

Methods and devices for treating primary headache


Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache.
Electrocore, Llc


05/05/16
20160120965 

Vaccine peptide combinations against cat allergy


The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides. .
Circassia Limited


04/28/16
20160114031 

Recombinantly produced allergens


Methods for producing an allergen composition, methods for in vitro diagnosis of type i allergy, and diagnostic kits for performing diagnosis employ bos d 23k allergen of seq id no: 4, or the mature protein thereof, or a variant or fragment of the bos d 23k allergen or the mature protein sharing epitopes for antibodies with the bos d 23k allergen or the mature protein. Methods for treatment of a type i allergy to a mammal and pharmaceutical compositions employ a bos d 23k allergen of seq id no: 4, or the mature protein thereof, or a variant or fragment of the bos d 23k allergen or the mature protein sharing epitopes for antibodies with the bos d 23k allergen or the mature protein, wherein the bos d 23k allergen, the mature protein, the variant or the fragment is modified to abrogate or attenuate its ige binding response..
Phadia Ab


04/21/16
20160106831 

Beverage compositions and other formulations for treating allergies and methods for making the same


A composition for preventing and/or alleviating an allergy related condition and methods of making such compositions are disclosed herein. A composition in accordance with a particular embodiment can include honey having pollen derived from a known plant species and/or from a known geographic location.

04/07/16
20160095448 

Breathable mattress pad and sleeping accessories


Sleeping accessories such as mattress pads, mattress topper covers, and sheet savers are disclosed herein comprising integrated padded mesh material. Integrated padded mesh material, when used in the sleeping accessories, results in improved air flow for the user, which can reduce complications during sleep such as sudden infant death syndrome.
Breathablebaby, Llc


03/24/16
20160083466 

Anti-il-25 antibodies and uses thereof


The present invention provides antibodies that bind to human interleukin-25 (il-25) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human il-25 with high affinity.
Regeneron Pharmaceuticals, Inc.


03/24/16
20160082101 

Horse allergen and methods


A method for performing in vitro diagnosis of type 1 allergy, comprises contacting an immunoglobulin-containing body fluid sample from a patient suspected of having type 1 allergy with an immobilized horse allergen immobilized on a solid support, and detecting the presence, in the sample, of ige antibodies specifically binding to the horse allergen, wherein the presence of such ige antibodies specifically binding to the horse allergen is indicative of type 1 allergy. A method for treatment of type 1 allergy comprises administering to an individual susceptible to such treatment, the horse allergen, or a form of the horse allergen that is modified to abrogate or attenuate its ige binding response.
Phadia Ab


03/10/16
20160069858 

Rapid allergy testing method


The present invention provides a method for testing an allergy capable of rapidly and highly accurately testing an allergic reaction. The method can determine whether or not a patient has an allergy or whether or not an agent that may be allergenic to a patient has an allergenicity (an allergic reactivity) in the patient.

03/03/16
20160060367 

Refined product obtained from rice hull and preparation process and use thereof


Disclosed herein is a refined product obtained from a rice hull, which consists essentially of a type ii arabinogalactan having a number average molecular weight in the range of 56 to 103 kda. Also disclosed are a process for producing the refined product and use of the refined product for enhancing the biological activity of innate immune cells, as well as for treating allergy and cancer..
China Medical University


02/25/16
20160053270 

Rnai-mediated inhibition of histamine receptor h1-related conditions


Rna interference is provided for inhibition of histamine receptor h1 mrna expression, in particular, for treating patients having an hrh1-related condition or at risk of developing an hrh1-related condition such as allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma, or allergy.. .
Arrowhead Research Corporation


02/25/16
20160051666 

Novel prostate kallikrein allergen


Methods for treatment of a type i allergy in a mammal comprise administering to an individual in need of such treatment a polypeptide of seq id no: 1 or the mature protein, amino acids 25-260, of the polypeptide of seq id no: 1, or a fragment of the polypeptide or the mature protein, which fragment shares epitopes for antibodies with the polypeptide or the mature protein, respectively, or a hypoallergenic form thereof that is modified to abrogate or attenuate its ige binding response. Diagnostic kits comprise the polypeptide of seq id no: 1 or the mature protein, amino acids 25-260, of the polypeptide of seq id no: 1, immobilized on a solid support..
Phadia Ab


02/25/16
20160051417 

Urine detection inductor suitable for large-scale production


A detector for wet diaper is suitable for large-scale production. The detector comprises a nonwoven fabric (1) and at least two electrodes (2, 3) which are carbon powder coated on the nonwoven fabric (1).

02/04/16
20160030554 

Tolerogenic synthetic nanocarriers for allergy therapy


Disclosed are synthetic nanocarrier compositions, and related methods, comprising immunosuppressants and mhc class ii-restricted epitopes of an allergen that provide tolerogenic immune responses specific to the allergen.. .
Selecta Biosciences, Inc.


01/28/16
20160022539 

A prefilled medication device, making and using the same


The invention generally relates to prefilled disposable medication devices, method of making, and using to store, contain and deliver at least a diluent for allergenic extract and more particularly to a prefilled cartridge containing a diluent for allergenic extract for use with an injection pen for allergy treatments.. .
Phd Preventive Health Care And Diagnostics, Inc.


01/21/16
20160015821 

Glycotargeting therapeutics


Glycotargeting therapeutics are useful in the treatment of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent.. .
Anokion Sa


01/21/16
20160015794 

Topical ocular preparation of botulinum toxin for use in ocular surface disease


A composition of botulinum toxin is claimed which can penetrate into the ocular surface inclusive of a penetration through a conjunctiva, cornea, and other structures. This composition allows for a maximal penetration of a topical preparation of botulinum toxin which serves to reduce the need for frequent allergy drops for the treatment of ocular surface disease and other conditions causing ocular surface inflammation or deep ocular inflammation.
Botulinum Toxin Research Associates, Inc.


01/21/16
20160015630 

Sprayable oxygenated saline composition and treating nasal congestion, allergy, dryness, eye irritation, throat irritation, wounds, and skin as applied to human tissues


An oxygenated saline composition is provided comprising stabilized oxygen, sodium chloride (aqueous saline solution), and optionally one or more homeopathic components. The stabilized oxygen can include quad-atomic oxygen.
Oxy Bump Corporation


12/03/15
20150344934 

Novel high throughput assay for finding new jak3 interacting compounds, biomolecules, and inhibitors.


Janus kinase 3 is a non-receptor tyrosine kinase that mediates signals initiated by cytokines through interactions with the receptors of cytokines. Abnormal activation of jak3 was associated with human hematologic and epithelial malignancies.

12/03/15
20150344908 

Method of genetically altering and producing allergy free cats


A transgenic cat with a phenotype characterized by the substantial absence of the major cat allergen, fel d i. The phenotype is conferred in the transgenic cat by disrupting the coding sequence of the target gene with a specialized construct.

12/03/15
20150342514 

System and multiple allergen testing


The testing apparatus includes a capsule 108 tray and a hand held allergen applicator 104 that facilitates convenient storage and easy application of such allergens simultaneously. The hand held applicator 104 includes a plurality of prongs to administer the respective plurality allergen under the skin of the patient.

11/26/15
20150335735 

Peptide carrier fusion proteins as allergy vaccines


The present invention relates to a polypeptide comprising at least three peptide fragments consisting of 10 to 50 consecutive amino acid residues of at least one wild-type allergen fused to the n- and c-terminus of a surface polypeptide of a virus of the hepadnaviridae family or at least one fragment of said surface polypeptide.. .
Biomay Ag


11/19/15
20150329864 

Design of oligonucleotide analogs as therapeutic agents


It is believed that the compounds and compositions as described herein have therapeutic utility against a variety of diseases, including viral diseases, autoimmune diseases (such as, allergy, asthma, and inflammatory disorders) and cancer.. .

11/19/15
20150329624 

Igy composition for use in celiac disease


The present invention relates to an igy composition characterized in that said igy composition contains igy antibodies, fragments, and/or fab fragments thereof that specifically bind to a peptide with the amino acid sequence of seq id no: 1 and to the use of this igy composition in the therapy of celiac disease, rheumatism, and/or wheat allergy.. .
Charite - Universitatsmedizin Berlin


11/19/15
20150328294 

Novel immunotherapeutic molecules and uses thereof


The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with t lymphocytes in subjects having peanut allergy, or allergy to other tree nuts, and genetic sequences encoding same. These molecules are preferably immunointeractive with t cells in subjects having an allergy to the ara h 1 allergen.
Health, Alfred


11/19/15
20150327576 

Animal food composition and process for production


An animal food composition comprising a protein source and corn starch, wherein native high-amylose corn starch comprises at least 50% of the corn starch. The composition can be used to treat or prevent a food allergy in an animal.
Hill's Pet Nutrition, Inc.


10/29/15
20150306211 

Process for producing an allergen extract


The present invention discloses processes for producing native, depigmented and polymerised allergen extracts. The invention further discloses extracts produced via the processes, and pharmaceutical and vaccine compositions comprising the extracts, for diagnosis and treatment of allergy..
Laboratorios Leti, S.l.


10/29/15
20150306146 

Methods of treating or preventing respiratory conditions


The present disclosure provides methods of treating or preventing respiratory condition and/or for treating an ige-mediated allergy and/or for reducing an allergic response to an allergen and/or for inducing anergy to an allergen in a subject and/or improving lung function in a subject suffering from an allergy comprising administering to a subject a population of cells enriched for stro-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.. .
Mesoblast, Inc.


10/22/15
20150299294 

New fusion proteins for the treatment of allergic diseases


The present invention relates to a fusion protein comprising a first peptide and a second peptide linked together with a linker, wherein the first peptide is an allergen and the second peptide is a targeting unit and the targeting unit is a fgl-2 c-terminal peptide according to seq id no 1. Provided herein are also uses of said fusion protein as a vaccine for treating allergy, such as shrimp, peanut or mite allergy, as well as a vaccine composition and methods for producing such fusion proteins..
Veteriaerinstituttet


10/22/15
20150297703 

Bifidobacterium for dust mite allergy


A composition comprising bifidobacterium breve for use in improving lung function in human subjects suffering from dust mite allergy.. .
N.v. Nutricia


10/22/15
20150297641 

Allergy treatment using acid treated aqueous whey protein extract


The invention relates to manufacture of whey protein extracts, to infant formula and to reducing or preventing food allergy. The whey protein extract is produced from a whey protein-containing composition by contacting a whey protein-containing composition with an aqueous solution to form a sample including a soluble protein-containing component and an insoluble component; recovering the soluble protein-containing component from the sample; and acidifying the soluble protein-containing component, thereby producing the whey protein extract.
Women's And Children's Health Research Institute


10/22/15
20150297129 

System and automatic reading of an allergy


A system and method for automatic reading skin for an allergy to a substance, includes a consumer electronics device that acquires images of skin; a consumable member having a surface divided into elementary areas, each elementary area with a different possible allergenic substance; and a palette that, when applied against each elementary area brings the depositing part into contact with the skin thereby depositing the corresponding possible allergenic substance on or under the skin, where an image processing operation of the image of the skin taken by the consumer electronics device localizes the location that each depositing part has deposited the possible allergenic substance during the application and provides information in relation with a sensitivity of the skin, as indicated by a visible reaction, to the possible allergenic substance at each localized location.. .
Ergylink


10/15/15
20150289794 

Allergy skin test applicator, and related testing tray, testing kit and testing method


An allergy testing kit contains a plurality of allergy testing applicators, an allergy testing tray and a plurality of allergen bottles each containing an allergen. Each of the applicators contains an elongated handle, a plurality of arms extending from the elongated handle and disposed in an asymmetrical configuration, and a plurality of legs with tines extending from each of the arms.

10/01/15
20150276757 

Wheat proteomic microarray for biomarker discovery


This invention pertains to the preparation of arrays containing the proteome of wheat, including gluten and non-gluten proteins. Antibodies to wheat gluten have been shown to be elevated, not only in celiac disease and wheat allergy, but also in neuropsychiatric disorders, such as schizophrenia, bipolar disorder, and autism.
The Trustees Of Columbia University In The City Of New York


10/01/15
20150273115 

M cells and artificial skin sheet


[problem] to provide m cells having excellent strength and anti-allergy activity and an artificial skin sheet formed from the m cells. [solution] gp2 contained in the m cells is transferred to the intracellular tight junction and galectin 9 is expressed in the m cells.

09/24/15
20150265198 

Plastic blood lancet


The present invention provides a surgically invasive pointed article for skin penetration and capillary whole blood extraction whose penetration ability can be disabled after use by deforming the tips. The present invention is made by injection moulding a plastic needle 35 having an anchoring means 45 using a first material, followed by another injection moulding process to over-mould a first body segment 20 and second body segment 30 using a second material to encase the plastic needle 35 thereby anchoring the plastic needle 35 to prevent further movement of the plastic needle 35.

09/10/15
20150250870 

Compositions for immunotherapy


The present invention relates to compositions which can be used in immunotherapy and especially to compositions which can be used in immunotherapy for mammals suffering from a peanut allergy. The present invention further relates to the use of the present compositions for the treatment of a mammal suffering from an allergy by immunotherapy and the use of the present compositions in a prophylactic treatment for desentizing the immune system of a mammal for an allergen.
Hal Allergy Holding B.v.


09/10/15
20150250220 

Nutritional compositions containing ceramide and uses thereof


The present disclosure relates to nutritional compositions that include at least one ceramide. The nutritional compositions may further include galactose, sialic acid, or cholesterol.
Mead Johnson Nutrition Company


09/03/15
20150246889 

Benzimidazole derivatives as pi3 kinase inhibitors


This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ oh kinase family (hereinafter pi3 kinases), suitably, pi3kα, pi3kδ, pi3kβ, and/or pi3kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries.
Glaxosmithkline Llc


08/27/15
20150239886 

Substituted fused tricyclic compounds, compositions, and medicinal applications thereof


The compounds of the present invention are useful in the treatment, prevention or suppression of diseases and disorders mediated by jak activity. Such conditions include, but not limited to, arthritis, alzheimer's disease, autoimmune thyroid disorders, cancer, diabetes, leukemia, t-cell prolymphocytic leukemia, lymphoma, myleoproliferation disorders, lupus, multiple myeloma, multiple sclerosis, osteoarthritis, sepsis, psoriatic arthritis, prostate cancer, t-cell autoimmune disease, inflammatory diseases, chronic and acute allograft transplant rejection, bone marrow transplant, stroke, asthma, chronic obstructive pulmonary disease, allergy, bronchitis, viral diseases, or type i diabetes, complications from diabetes, rheumatoid arthritis, asthma, crohn's disease, dry eye, uveitis, inflammatory bowel disease, organ transplant rejection, psoriasis and ulcerative colitis.

08/27/15
20150238581 

Novel histamine releaser contained in human sweat


Provided arc a sweat allergy antigen, an antibody capable of binding to the antigen specifically, and others, which are produced utilizing a microorganism-originated protein that exists in sweat allergy patient in a dissolved state or a partial peptide of the protein.. .
Hiroshima University


08/20/15
20150231234 

Use of anti-cd1 antibodies for the modulation of immune responses


The invention provides methods for the administration of an anti-cd1 antibody for the treatment or prevention of a variety of disorders, such as autoimmune disease, viral infection, bacterial infection, parasitic infection, infection by a eukaryotic pathogen, allergy, asthma, inflammatory condition, graft versus host disease, graft rejection, immunodeficiency disease, spontaneous abortion, pregnancy, and cancer.. .
Beth Israel Deaconess Medical Center, Inc.


08/13/15
20150225398 

Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders


Useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons.. .

08/13/15
20150224199 

Pharmaceutical compositions for the treatment of inflammatory disorders


Useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons.. .

08/13/15
20150224153 

Probiotics for use in reducing eosinophilia and respiratory allergies


The present invention provides probiotic compositions suitable for reducing the incidence and duration of nasal eosinophilia and other parameters associated with birch pollen allergy. In some embodiments, the present invention provides methods and/or compositions suitable for reducing nasal and/or respiratory allergy symptoms..
Dupont Nutrition Biosciences Aps


08/06/15
20150218563 

Compositions and methods for modulation of rorgammat functions


The present invention relates to expression of rorγt in cells and tissues and the effect of expression of this gene on proliferation of specific immune cells and in promotion of immune cell aggregates and in induction of il17 producing cells. Furthermore, the invention relates to methods and agents that may decrease function of the gene product (the protein) or expression of this gene in individuals experiencing an inflammatory condition, an autoimmune disease or a food allergy, or any other condition whereby it is desirable to inhibit an immune response.

08/06/15
20150218215 

Cladosporium peptides


Polypeptides which may be used for preventing or treating allergy to moulds of the cladosporium and/or alternaria genus, have up to 30 amino acids in length and comprise: (i) the amino acid sequence: (a) ggykaavrptmle (seq id no: 35; cla35), (b) ae v yqklk sltkk (seq id no: 31; cla16), (c) vaityasraqgae (seq id no: 32; cla25), (d) ghhfkergt-gslvit (seq id no: 33; cla26), or (e) anytqtktvsirl (seq id no: 34; cla29); or (ii) a t cell epitope-containing variant sequence which is a said amino acid sequence (i) having up to six amino acid modifications, each of which is independently a deletion, substitution or insertion.. .
Circassia Limited


08/06/15
20150216470 

Allergy testing device and testing for allergies


An allergy testing system comprises a skin test device having a grip portion for holding the device. One or more legs extend from the grip, and each leg is oriented to interact with a well containing a potential allergen.
Lincoln Diagnostics, Inc.


07/30/15
20150212097 

Monoclonal lge antibody that binds to sweat allergy antigen protein


Provided include a human ige antibody that binds to a sweat allergy antigen protein and a human high-affinity ige receptor but does not induce degranulation in a reaction with the sweat allergy antigen protein, and a composition for treatment or diagnosis of sweat allergy comprising the same.. .
Hiroshima University


07/30/15
20150210742 

Novel allergen from ragweed pollen and uses thereof


The present invention notably concerns a novel major allergen from ragweed pollen, named amb a x, as well as isoallergens and isoforms thereof. Fragments of the aforementioned polypeptides and homologous polypeptides, in particular homologous polypeptides in related plant species, also make part of the invention.
Stallergenes S.a.


07/30/15
20150209410 

Compositions and methods relating to the treatment of diseases


A method is provided for the treatment and/or prophylaxis of a condition where an enhancement of a th1-mediated immune response and suppression of a th2/th17-mediated immune response are desired. The method comprises the step of administering to a subject in need thereof a therapeutically effective amount of at least one interferon alpha subtype selected from ifn-α10, ifn-α14, and a hybrid thereof.
Alfacyte, Ltd.


07/23/15
20150203537 

Inhibition of gliadin peptides


Novel compounds and methods for the inhibition of biological barrier permeability and for the inhibition of peptide translocation across biological barriers are identified. Assays for determining modulators of biological barrier permeability and for peptide translocation across biological barriers are provided.
Alba Therapeutics Corporation


07/16/15
20150196635 

Peptides for vaccine against birch allergy


The present invention relates to compositions comprising peptides for preventing or treating allergy to birch, and in particular to optimal combinations of peptides for preventing or treating said allergy.. .
Circassia Limited


07/16/15
20150196633 

Hypo-allergenic cross-linked proteins for use in the prevention of an allergy against milk-proteins and for use in the induction of oral tolerance


The present invention provides a hypo-allergenic cross-linked protein for use in the prevention of an allergy against milk proteins, or for use in the induction of oral tolerance for milk proteins, said cross-linked protein being selected from cross-linked casein, cross-linked caseinate and combinations thereof. The invention further provides a nutritional composition for use in the prevention of an allergy against milk proteins or for use in the induction of oral tolerance against milk proteins..
Friesland Brands B.v.


07/02/15
20150183848 

Treatment of lge-mediated disease


The methods and compositions described herein are based, in part, on the discovery of a polypeptide of soluble cd23 (scd23) that binds and sequesters ige. Thus, the scd23 peptides, polypeptides and derivatives described herein are useful for treating conditions or disorders involving increased ige levels such as e.g., allergy, anaphylaxis, inflammation, lymphoma, and certain cancers..
Trustees Of Boston University


06/25/15
20150175710 

Alpha-enolase specific antibodies and use in immune diseases


A method for treating an inflammatory disease or an immune disorder includes administering to a subject in need of such treatment an antagonist against eno1. The antagonist binds eno1 and inhibits eno1 plasminogen receptor activity.
Development Center For Biotechnology


06/25/15
20150174225 

Nanoparticles for treatment of allergy


The present invention encompasses the surprising finding that nanoparticle compositions can have beneficial effects on allergy even when prepared without a known specific allergy therapeutic. The present invention provides such nanoparticle compositions.
Allertein Therapeutics, Llc


06/11/15
20150158874 

Novel pyridopyrimidine derivatives and use thereof


The invention provides novel substituted pyridopyrimidines represented by formula i or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ oh kinase family (pi3k) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders..
Cmg Pharmaceutical Co., Ltd.


06/04/15
20150153358 

Materials and methods for diagnosing and treating shellfish allergy


The disclosure provides materials and methods for diagnosing, treating and preventing shellfish allergic reactions, including allergic reactions to shrimp. The technology involves one or more shellfish-specific proteins selected from the group of myosin light chain, sarcoplasmic calcium-binding protein, hemocyanin, fatty acid binding protein, and troponin c, for example from shrimp, as well as encoding polynucleotides, vectors host cells, and specific binding partners for such proteins, e.g., antibodies.
Icahn School Of Medicine At Mount Sinai


06/04/15
20150152148 

Hypoallergenic hybrid proteins of major group 1 and 2 mite allergens for use in the treatment of allergies


The present invention refers to recombinant and molecules coding to hybrids polypeptides of different allergens from d. Pteronyssinus useful for the prevention and treatment of allergies, particularly allergies caused by mites.
Bial Industrial Farmaceutica, S.a.


06/04/15
20150152138 

Uses of kappa opioid synthetic peptide amides


The invention relates to methods of use of synthetic peptide amides that are ligands of the kappa opioid receptor in the treatment and prevention of kappa opioid receptor-associated diseases and conditions; and particularly to uses of these agonists in the prophylaxis, inhibition and treatment of pain, inflammation and pruritis associated with a variety of diseases, disorders and conditions. Inflammatory conditions preventable or treatable by the methods of the invention include diseases and conditions associated with elevated levels of a proinflammatory cytokines, such as tnf-α, il-1β, il-6, mmp-1 and mmp-3.
Cara Therapeutics, Inc.


06/04/15
20150150926 

Composite with antibacterial and antipruritic functions


A composite with antibacterial and antipruritic functions includes a first substrate extracted from a plant, a second substrate and a base, and the first substrate includes a loniceraiaponica extract and an acanthopanax extract, and both loniceraiaponica extract and acanthopanax extract have a weight percentage ranging from 0.75 to 1.33, and the composite can effectively restrain the itch caused by skin pustules, folliculitis, and mosquito bites, and achieve the moisturization and antipruritic and anti-dander effects for mitigating the symptoms caused by candida albicans and staphylococcus aureus. In addition, this composite has good effects on general skin diseases such as hand eczema (ktpp), eczema, and lip herpes.
Li Tzu Pao Mei Regiman Beauty Public Ltd. Company


06/04/15
20150150925 

Wound healing composite with a function of promoting the growth of granulation tissues


A composite with antibacterial and antipruritic functions includes a first substrate extracted from a plant, a second substrate and a base, and the first substrate includes a loniceraiaponica extract and an acanthopanax extract, and both loniceraiaponica extract and acanthopanax extract have a weight percentage ranging from 0.75 to 1.33, and the composite can effectively restrain the itch caused by skin pustules, folliculitis, and mosquito bites, and achieve the moisturization and antipruritic and anti-dander effects for mitigating the symptoms caused by candida albicans and staphylococcus aureus. In addition, this composite has good effects on general skin diseases such as hand eczema (ktpp), eczema, and lip herpes.
Li Tzu Pao Mei Regiman Beauty Public Ltd. Company


06/04/15
20150150924 

Wound healing composite with a function of promoting the growth of granulation tissues


A wound healing composite with a function of promoting the growth of granulation tissues includes a substrate extracted from a plant and a base, and the substrate includes a loniceraiaponica extract, a mugwort extract, and ginkgo, and both loniceraiaponica extract and ginkgo have a weight percentage ranging from 0.28% to 3.5%. The wound healing composite can effectively promote the growth of granulation tissues, and loniceraiaponica, mugwort, ginkgo and other ingredients are extracts of natural plants, and thus the wound healing composite has a low drug resistance and does not have the side effect of drug allergy or the doubt leading to skin cancer..
Li Tzu Pao Mei Regiman Beauty Public Ltd. Company




Allergy topics: Autoimmune, Prophylactic, Ophthalmic, Autoimmune Disorder, Immune Disorder, Dermatitis, Staurosporin, Aspergillosis, Angioedema, Allergic Rhinitis, Food Allergy, Therapeutical, Bronchopulmonary, Staurosporine, Sudden Infant Death

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