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Allergy patents

      

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 Allergy testing device and  testing for allergies patent thumbnailAllergy testing device and testing for allergies
An allergy testing system comprises a skin test device having a grip portion for holding the device. One or more legs extend from the grip, and each leg is oriented to interact with a well containing a potential allergen.
Lincoln Diagnostics, Inc.


 Treatments of ocular allergy with alcaftadine patent thumbnailTreatments of ocular allergy with alcaftadine
Compositions, kits and methods for the treatment or prevention of ocular allergies and inflammation and the symptoms thereof comprising alcaftadine or a pharmaceutically acceptable salt thereof.. .
Vistakon Pharmaceuticals, Llc


 Allergen exposure system comprising a chamber for mixing air and allergens, which is separated from the exposure room that accommodates the patients patent thumbnailAllergen exposure system comprising a chamber for mixing air and allergens, which is separated from the exposure room that accommodates the patients
An allergen exposure system includes a mixing chamber, delimited by walls and distinct from the air inlet duct and from the exposure room in which the patients are situated. A mixing between a stream of allergen particles from an allergen injection device and a flow of air devoid of allergens which has passed through a filtration device, occurs through a phenomenon of microturbulence in this mixing chamber which forms a widening with respect to the air inlet duct and makes it possible to obtain a flow of air laden with allergen particles which is injected into the exposure room through at least one diffusion outlet so that it can be inhaled by the patients.
Alyatec


 Method for synthesis of a biopolymer derivative, a biopolymer derivative and its use patent thumbnailMethod for synthesis of a biopolymer derivative, a biopolymer derivative and its use
The invention relates to a method of synthesis of a biopolymer derivative, preferably a chitosan derivative, comprising the formation of a peptide bond. The invention also relates to the biopolymer derivative, and use of the biopolymer derivative, preferably a chitosan derivative.
Instytut Biochemii I Biofizyki Polskiej Akademii Nauk


 Treating infection patent thumbnailTreating infection
The present invention relates to surfactant protein d (sp-d) or nucleic acids encoding sp-d or variants thereof such as surfactant protein a or mannan binding lectin for use in the treatment and/or prevention of a parasitic infection. Methods for determining the presence of a parasitic infection by determining levels of sp-d in a sample are also disclosed.
University Of Cape Town


 Method of treating inflammation, allergy and asthma with a purified extract (atc1) isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient patent thumbnailMethod of treating inflammation, allergy and asthma with a purified extract (atc1) isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient
The present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a ova-sensitized/challenged mouse model..
Korea Research Institute Of Bioscience And Biotechnology


 Method of treating inflammation, allergy and asthma with a purified extract (atc2) isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient patent thumbnailMethod of treating inflammation, allergy and asthma with a purified extract (atc2) isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient
The present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a ova-sensitized/challenged mouse model..
Korea Research Institute Of Bioscience And Technology


 Methods of measuring antigen-specific t cells patent thumbnailMethods of measuring antigen-specific t cells
Provided herein are methods and kits for assaying antigen-specific t cell responses, such as rare autoantigen-specific t cell responses, by measuring a level of ip-10 in a sample from a subject having or suspected of having an autoimmune disease, an allergy, an infectious disease or condition, or an adverse immune condition caused by administration of an isolated, recombinant or synthetic protein or peptide. Also provided herein are methods and kits for assaying a t cell response to an antigen peptide, such as an islet autoantigen peptide, such as measuring a t cell response to at least one antigen peptide, such as an islet autoantigen peptide, in a sample from a subject, such as one having or suspected of having type 1 diabetes (tid), celiac disease or both..
Immusant, Inc.


 Individually customized allergy cream for individual patient profile patent thumbnailIndividually customized allergy cream for individual patient profile
A method for delivering an immunomodulator to a patient includes providing a bottle of concentrated immunomodulator extract; progressively diluting the antigen extract in sterile bottles; selecting a prescribed amount from a desired one of the dilution bottles; providing a viscous encapsulation material that is able to introduce antigens contained therein through the skin of a patient; introducing one or more doses of the selected prescribed amount of diluted immunomodulator into the viscous encapsulation material; disposing a prescribed amount of viscous encapsulation material containing the introduced diluted immunomodulator therein within a container that is able to dispense such viscous encapsulation material containing the introduced diluted immunomodulator; dispensing from the container the amount of viscous encapsulation material containing the diluted immunomodulator in an amount equal to a single dose; and applying the dispensed viscous encapsulation material containing the introduced diluted immunomodulator to the skin by the patient or a medical professional.. .
Roca Medical Ltd.


 Implantable device for automatic delivery of medication for allergic reactions patent thumbnailImplantable device for automatic delivery of medication for allergic reactions
Apparatus, implanted subcutaneously or in muscle, fat, joint spaces, or body cavities of any type, detects and responds to an allergic and/or anaphylactic reaction. Detection is carried out by monitoring the levels of biomarker molecules that indicate the occurrence of an allergic and/or anaphylactic reaction, such as: histamine, leukotrienes, prostaglandins, cytokines, tryptase, fc-ε-ri complexes, anaphylatoxin c3a, chymase, carboxypeptidase a, platelet-activating factor8, other mast cell degranulation byproducts, or other basophil activation compounds.

Compositions and methods for treating itching, gingivostomatitis, and demodectic mange

Provided are methods for treating itching caused by allergy, include itching associated with parasite-mediated inflammation (e.g., demodicosis, stomatitis, dermatophytosis, etc.), comprising administration to a mammalian subject in need thereof a therapeutically effective amount of a heat-treated, fractionated thymus extract composition (e.g., thyex-1-6a and -6b compositions, comprising proteins or polypeptides having molecular weights in the range of 3.5 kda to 30 kda), in combination with or formulated with colostrum, to provide for reducing itching in the subject. Combination or adjunctive therapies comprising administration of a heat-treated, fractionated thymus extract composition in combination with or formulated with colostrum, and including at least one additional anti-parasitic, anti-bacterial, anti-fungal, anti-viral agent, or homeopathic agent are also provided.
Cmi Research Management, Llc

Medical software platform

A medical system is disclosed for retrieving and recording information from a patient and generating an efficient and effective clinical report encompassing the relevant data for a practitioner's review. The system may also include one or more communication paths for receiving additional information such as from patient wearables, environmental sensors, medication dispensers, whether sources, allergy sources, and other geographic relevant environmental conditions, contaminants, conditions, traffic congestion, etc..
Victaire Inc.

Nkt cell ligands and methods of use

Alpha-glycosylceramide compounds capable of activating nkt cells and compositions thereof are disclosed. Methods for activating nkt cells, methods of stimulating an immune response in a subject, and methods of treating cancer, infectious diseases, autoimmune diseases and disorders, or allergy diseases or disorders with the compounds and compositions are also disclosed..
Brigham Young Unversity

Purified extract isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient, the preparation thereof, and the composition comprising the same as an active ingredient for preventing or treating inflammation, allergy and asthma

The present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a ova-sensitized/challenged mouse model..
Korea Research Institute Of Bioscience And Biotechnology

Method for manufacturing fermented food composition

According to a manufacturing method of the present invention, class 2 food allergens can be decomposed even if a protease is not used, and thus a manufacturing cost is inexpensive, and a food composition having a reduced content of class 2 food allergens can be provided without using salt water which has an effect on the taste. The fermented food composition, obtained by the manufacturing method of the present invention, has a sufficiently reduced content of the class 2 food allergens, and thus even those who contracts pollinosis or latex allergy can safely take it.
Kaneka Corporation

Allergy preventing dosage controlled food packets

A kit of individual packets of food containing a dosage amount of an allergen. The kit has a plurality of packets associated with each other and containing a carrier food in each packet and an allergen so arranged that the respective allergen quantity in each successive packet is larger than in the previous packet.

Interleukin-2 for treating food allergy

The present invention relates to the use of interleukin-2 (il-2) for treating a food allergy, either by inducing non-specific tolerance against food allergens, or in a desensitization protocol, in combination with a food allergen.. .
Centre National De La Recherche Scientifique

Compositions and methods for combination ingredient delivery

Described herein are compositions, methods, and devices for relief of a cough, cold, sore throat, or allergy, or a related symptom. Also described herein are compositions, methods, and devices for the prevention, treatment and/or amelioration of a digestive illness or digestive discomfort, or a related symptom of either..
The Fix, Llc

Vaccine comprising amb a 1 peptides for use in the treatment of ragweed allergy

The present invention relates to compositions for preventing or treating allergy to ragweed by tolerisation. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, amb a 1.
Circassia Limited

Screening the identification of agents capable of activating cd4+cd25+ regulatory t-cells through interactions with the hiv-1 gp120 binding site on cd4

The present invention relates specific activation of a regulatory t cell via a specific cd4 epitope and uses thereof, e.g. For the treatment of an autoimmune disease or an allergy or asthma or graft rejection or tolerance induction..
Tcf Gmbh

Use of escin

The present invention provides the use of escin for the manufacture of a pharmaceutical preparation for the treatment diseases mediated or caused by activated granulocytes, preferably a type i or type iii allergy or septic shock.. .
Marinomed Biotechnologie Gmbh

Benzazepine dicarboxamide compounds

Wherein r1 to r4 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are tlr agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases..

Glycotargeting therapeutics

Several embodiments of the present disclosure relate to glycotargeting therapeutics that are useful in the treatment of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent. In several embodiments, the compositions are configured to target the liver and deliver antigens to which tolerance is desired.
École Polytechnique Fédérale De Lausanne (epfl)

Allergy skin test devices

An allergy skin test device can include a support strip having a top and bottom face. An allergen can be applied to an area of the bottom face forming an allergen portion.
Rememdia Lc

Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons.. .

Novel immunotherapeutic composition and uses thereof

The present invention relates generally to an immunotherapeutic composition. More particularly, the present invention relates to an immunotherapeutic composition which interacts immunologically with t lymphocytes in subjects having peanut allergy or allergy to other tree nuts.
Aravax Pty Ltd

Newly identified peptides for use in the induction of oral tolerance in young mammals

The invention relates to newly identified peptides of that are capable of inducing tolerance to cow's milk, especially to β-lactoglobulin. The peptides may be administered to mammals, especially to young infants who are at risk of allergy to cow's milk proteins, to induce oral tolerance to cow's milk; they may also be administered to children or adults who are allergic to cow's milk to allow “desensitization” towards the allergenic milk proteins, especially β-lactoglobulin, to occur.
Nestec S.a.

C1q as a therapeutic agent of allergy and/or asthma

The present invention concerns c1q for use for treating allergy and/or asthma. The invention also relates to a pharmaceutical composition comprising c1q and at least one allergen and to products comprising c1q and at least one allergen as a combined preparation for use for treating allergy and/or asthma..
Stallergenes

Contact thermo-optical structure and its application for non-invasive imaging of histamine-induced hyperthermal subcutaneous reaction magnitude in cutaneous allergic reaction, recording device and allergic reaction diagnosis

A method of diagnosing allergy according to the invention comprises the steps of stimulation, measurement and comparison. The stimulation step includes at least exposition of a first region of patient's skin to a histamine solution, exposition of a second region of patient's skin to a neutral solution and exposition of a third region of patient's skin to a test substance.

Novel histamine releaser contained in human sweat

Provided are a sweat allergy antigen, an antibody capable of binding to the antigen specifically, and others, which are produced utilizing a microorganism-originated protein that exists in sweat allergy patient in a dissolved state or a partial peptide of the protein.. .
Hiroshima University

Mimotopes for use in immunotherapy for shellfish and/or arthropod allergy

The present invention provides isolated peptides and nucleic acids encoding the isolated peptides that can modify a subject's immune response to tropomyosin. The isolated peptides correspond to peptide epitope mimics that are based on an invertebrate tropomyosin allergen, e.g., the shrimp tropomyosin met e 1.
The Chinese University Of Hong Kong

Effector-deficient anti-cd32a antibodies

Effector-deficient anti-cd32a monoclonal antibodies are encompassed, as are method and uses for treating cd32a-mediated diseases and disorders, including, thrombocytopenia, allergy, hemostatic disorders, immune, inflammatory, and autoimmune disorders.. .
Adventist Health System/sunbelt Inc.

Air purification method and apparatus

An air purification method for use in an apparatus is provided. The air purification method includes: acquiring plant information associated with one or more plants located in a target detection region; determining, based on the plant information and predetermined reference plant information of an allergy-causing plant, that the target detection region contains the allergy-causing plant and the allergy-causing plant is in a blooming state; and in response to the determining, enabling an air purification function of an air purification device..
Xiaomi Inc.

Sirp polypeptide compositions and methods of use

Provided herein are sirp-gamma, sirp-beta or sirp-beta2 decoy polypeptides for immunotherapy and/or treatment of cancer, anemia, transplant, asthma, allergy, auto-immune disease, and viral infection.. .
Ab Initio Biotherapeutics, Inc.

Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor

Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by h4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.. .
Janssen Pharmaceutica Nv

Method and means for diagnosing and treating allergy

Disclosed is a method for diagnosing allergy in a human or animal patient, wherein the level of species-specific lipocalin, especially lipocalin 2 in a human patient, is measured in a sample of said patient and wherein a lowered level of said lipocalin compared to the level of said lipocalin in the corresponding sample of a human or animal that has no allergy, is indicative of an allergy, as well as a kit for performing this method, and a kit for quality control of allergen molecules or extracts used for immunotherapy of allergy by determining its siderophore-iron ligand load and thus immunomodulatory potency. Further, lipocalin proteins for use in treatment or prevention of allergies are provided, preferably complexed with siderophore-iron ligands..
Biomedical International R+d Gmbh

Methods and devices for allergy testing and treatment

A method of testing a patient for allergies includes obtaining from the patient a blood sample having an original volume of at most 0.5 ml, and testing the blood sample for ige reactive with antigens from a plurality of allergen sources by multiple elisa. The blood sample may be taken from the patient in a clinic, and/or the blood sample may be taken by a physician without venipuncture.
Spiriplex, Inc

Method of preventing allergies

The present invention relates to compositions and methods for preventing allergy in a subject. Particularly, the present invention relates to epicutaneous prevention of allergies in children.
Dbv Technologies

Supplement for improving immunotolerance, intestinal environment and intestinal tract barrier

A supplement for improving immunotolerance, intestinal environment and intestinal tract barrier for the purpose of improving intestinal vulnerability, food intolerance or allergy, systemic allergy, autoimmune diseases and systemic inflammatory diseases by immune reactions which is obtained by mixing an ingredient (a) comprising at least one of a probiotic that is any one of lactic acid bacteria, lactobacillus bifidus, saccharified bacteria, natto bacteria and yeast fungus, or a mixture thereof, a biogenic that is a bacteria-producing substance such as lactic acid bacteria, and a prebiotic is indigestible food ingredients such as oligosaccharide, dietary fiber, substance stimulating production of lactobacillus bifidus, and others or a mixture thereof and an ingredient (b) comprising at least one of l-glutamine, zinc, vitamin a and vitamin d.. .

Treatment of celiac disease, c. difficile infection, food intolerance and food allergy with secretory iga/igm

A process is provided for inhibiting symptoms of celiac disease, clostridium difficile associated diseases such as clostridium difficile colitis, pseudomembranous colitis and antibiotic associated diarrhea, food allergy or food intolerance in a subject that includes the oral adminstration to the subject suffering from food allergy or food intolerance an igm. When administered in a, therapeutic quantity based on the subject characteristics and the type of igm, symptoms of food allergy or food intolerance in that subject are inhibited.

Programming of cells for tolerogenic therapies

Biomaterial systems, e.g., gel scaffolds, are used in vivo to recruit immune cells and promote their activation towards a non-inflammatory phenotype, thereby leading suppression of inflammation. The compositions and methods are useful to reduce the severity of autoimmunity, chronic inflammation, allergy, and periodontal disease..
Forsyth Dental Infirmary For Children

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit tlr-mediated signaling in response to a tlr ligand or tlr agonist.
Idera Pharmaceuticals, Inc.

Methods for treating allergic airway inflammation

Provided herein are methods for treating a symptom and/or clinical sign associated with an allergy that includes neutrophil recruitment, such as allergic airway inflammation. In one embodiment, the method includes administering to a subject a composition that includes a cxcr2 inhibitor, a md2 inhibitor, a myd88 inhibitor, or a combination thereof.



Allergy topics:
  • Autoimmune
  • Prophylactic
  • Ophthalmic
  • Autoimmune Disorder
  • Immune Disorder
  • Dermatitis
  • Staurosporin
  • Aspergillosis
  • Angioedema
  • Allergic Rhinitis
  • Food Allergy
  • Therapeutical
  • Bronchopulmonary
  • Staurosporine
  • Sudden Infant Death


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