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Alkyne patents



      
           
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Date/App# patent app List of recent Alkyne-related patents
04/17/14
20140107327
 Methods for preparing deuterated 1,2,3-triazoles patent thumbnailnew patent Methods for preparing deuterated 1,2,3-triazoles
This disclosure relates to a method that involves reacting an azide with an alkyne in the presence of deuterated water and a copper-containing catalyst, thereby forming a deuterated 1,2,3-triazole.. .
04/10/14
20140100198
 Enzyme inhibiting compounds and methods patent thumbnailEnzyme inhibiting compounds and methods
The invention provides compounds, compositions, and methods for studying the rohmer pathway and for treating bacterial infections or parasitic infections. The parasitic infection can be a protozoan infection, such as malaria.
04/10/14
20140099573
 Photoinitiated olefin methathesis polymerization patent thumbnailPhotoinitiated olefin methathesis polymerization
The present invention provides photosensitive compositions and methods of patterning a polymeric image on a substrate, said methods comprising; (a) depositing a layer of photosensitive composition of any one of claims 15 to 22 on the substrate; and (b) irradiating a portion of the layer of photosensitive composition with a light comprising a wavelength in a range of from about 220 to about 440 nm. The invention also relates to methods of metathesizing an unsaturated organic precursor comprising irradiating fischer-type carbene ruthenium catalysts with at least one wavelength of light in the presence of at least one unsaturated organic precursor so as to metathesize at least one alkene or one alkyne bond..
04/03/14
20140094599
 Cellulose ethers having reactive anchor group, modified cellulose ethers obtainable therefrom and methods for the preparation thereof patent thumbnailCellulose ethers having reactive anchor group, modified cellulose ethers obtainable therefrom and methods for the preparation thereof
Non-ionic water-soluble cellulose ethers modified with 3-azido-2-hydroxypropyl groups bound via an ether link are provided having a molar degree of substitution msahp in the range from 0.001 to 0.50. Exemplary cellulose ethers are alkyl celluloses, including methyl, hydroxyalkyl (e.g.
03/27/14
20140088112
 Alkyne benzotriazole derivatives patent thumbnailAlkyne benzotriazole derivatives
The present invention is directed to alkyne benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mglur2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved..
03/06/14
20140066632
 Copper-catalysed ligation of azides and acetylenes patent thumbnailCopper-catalysed ligation of azides and acetylenes
A copper catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to provide 1,4-disubstituted 1,2,3-triazole triazoles. The process comprises contacting an organic azide and a terminal alkyne with a source of reactive cu(i) ion in human blood plasma to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole.
02/27/14
20140058149
 High efficiency processes for olefins, alkynes, and hydrogen co-production from light hydrocarbons such as methane patent thumbnailHigh efficiency processes for olefins, alkynes, and hydrogen co-production from light hydrocarbons such as methane
High efficiency processes for producing olefins, alkynes, and hydrogen co-production from light hydrocarbons are disclosed. In one version, the method includes the steps of combusting hydrogen and oxygen in a combustion zone of a pyrolytic reactor to create a combustion gas stream, transitioning a velocity of the combustion gas stream from subsonic to supersonic in an expansion zone of the pyrolytic reactor, injecting a light hydrocarbon into the supersonic combustion gas stream to create a mixed stream including the light hydrocarbon, transitioning the velocity of the mixed stream from supersonic to subsonic in a reaction zone of the pyrolytic reactor to produce acetylene, and catalytically hydrogenating the acetylene in a hydrogenation zone to produce ethylene.
02/13/14
20140045207
 Compositions and methods for modification of biomolecules patent thumbnailCompositions and methods for modification of biomolecules
Provided are modified cycloalkyne compounds; and methods of use of such compounds in modifying biomolecules. Embodiments include a cycloaddition reaction that can be carried out under physiological conditions.
02/06/14
20140038826
 Covalently cross linked hydrogels and methods of making and using same patent thumbnailCovalently cross linked hydrogels and methods of making and using same
A thiol-yne polymeric material and methods for producing said polymers are disclosed. The material is produced by the radically mediated polymerization of monomers having alkyne and thiol functional groups.
01/30/14
20140031506
 Solution phase polydiacetylene synthesis by alkyne metathesis patent thumbnailSolution phase polydiacetylene synthesis by alkyne metathesis
The present disclosure provides compositions for alkyne metathesis catalysts and methods for preparing enediynes and alkyne metathesis catalysts. The disclosure also provides methods for catalyzing alkyne metathesis reactions and polymerization of enediyne substrates to polydiacetylenes in solution-phase..
01/23/14
20140024860
Method for hydroformylation of unsaturated compounds
The invention relates to a method for hydroformylation of unsaturated compounds such as olefins and alkynes using mixtures of synthesis gas (co/h2), in which either the unsaturated compounds and a catalyst are heated to a reaction temperature of 60 to 200° c. And the synthesis gas is then added, or the unsaturated compounds and the catalyst are brought into contact with pure co at normal temperature in a preformation step, then are heated to reaction temperature and on reaching the reaction temperature the co is replaced by the synthesis gas.
01/23/14
20140024815
Dendrimers with interior and exterior functionalities comprising of azide or alkyne groups for post-functionalization by huisgen click cycloaddition
A dendritic structure includes a core and repeating units, wherein the repeating units comprise units of the type abxcy, wherein x is 2, 3, or 4, wherein y is 1, 2, or 3, wherein c is selected from the group consisting of azides and alkynes, and wherein every repeating unit is bound to at least one other unit with at least one bond selected from the group consisting of the group consisting of an ester, an amide, a thioether, an ether, a urethane, an amine, and an imine. Advantages include that a “one-pot” growth of the dendritic structure is possible.
01/16/14
20140018541
Umsymmetrical bisazides for chemoselective sequential ligation
Unsymmetrical bisazides containing chelating and non-chelating azido groups undergo chemoselective three-component copper(i)-catalyzed azide-alkyne conjugation reactions with two different alkyne molecules. In conjunction with the reactivity gap between aromatic and aliphatic alkynes, a bistriazole molecule can be generated with an excellent regioselectivity by mixing two alkynes and a bisazide in a single reaction container.
01/16/14
20140014557
Process for desulphurization of petroleum oil
A process for desulphurization of petroleum oil, comprising the step of diluting the feed oil with a suitable organic solvent prior to the desulphurization reaction, is disclosed. The organic solvent is selected from alkanes, alkenes, cyclic alkenes and alkynes, and particularly selected from n-hexane, cyclohexane, heptane, pentene, hexene, heptene, octene, toluene and xylene.
01/09/14
20140012000
Process for preparing a propiolic acid or a derivative thereof
The invention relates to a process for preparing a propiolic acid or a derivative thereof by reacting a terminal alkyne with carbon dioxide, which comprises performing the reaction in the presence of a base and a copper complex, especially a copper (i) complex having at least one ligand, at least one of the ligands of the copper complex being selected from monodentate ligands which have an aminic or iminic nitrogen atom capable of coordination with copper, and polydentate ligands having at least two atoms or atom groups which are capable of simultaneous coordination with copper and are selected from nitrogen, oxygen, sulfur, phosphorus and carbene carbon.. .
01/02/14
20140005428
Metal-organic framework materials with ultrahigh surface areas
A metal organic framework (mof) material including a brunauer-emmett-teller (bet) surface area greater than 7,010 m2/g. Also a metal organic framework (mof) material including hexa-carboxylated linkers including alkyne bond.
01/02/14
20140005427
New (triorganosilyl)alkynes and their derivatives and a new catalytic method for obtaining new and conventional substituted (triorganosilyl)alkynes and their derivatives
The present invention relates to new (triorganosilyl)alkynes and their derivatives having general formula 1 r1—c≡c—z (i) in its second aspect, this invention relates to a new selective method for the preparation of new and conventional (triorganosilyl)alkynes and their derivatives having the general formula 1, by the silylative coupling of terminal alkynes with halogenotriorganosilanes in the presence of an iridium catalyst and a tertiary amine.. .
01/02/14
20140005408
Metal complexes, their application and methods of carrying out of metathesis reaction
This disclosure relates to new metal complexes, such as compounds of formula 1, and their application in olefin or alkyne metathesis and to methods of carrying out olefin metathesis reactions.. .
12/26/13
20130344527
Compositions and methods for modification of biomolecules
The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions.
12/19/13
20130338044
Bioconjugation using bifunctional linkers
A bifunctional linker and method of use is provided that has a spacer molecule with a functional group on one end configured to couple to the surface of a substrate and a function group on the other end that is configured couple to a biomolecule and methods of use. The preferred bifunctional linker has a poly(ethylene glycol) spacer ranging from 3 to 20 ethylene glycol units that has a silane functional group to react with a substrate and an azide functional group that can couple to a biomolecule that includes an alkyne group.
12/19/13
20130337435
M13 bacteriophage as a chemoaddressable nanoparticle for biological and medical applications
Reactive and modified m13 bacteriophages, and methods of making and using the same, are generally provided. The reactive m13 bacteriophage can include a alkyne functional group covalently attached to the m13 bacteriophage.
12/12/13
20130331593
Synthesis of treprostinil and intermediates useful therein
Treprostinil is prepared by a process which involves pauson-khan cyclization of an an alkene-substituted, alkyne-substituted benzene corresponding to formula: (i) where pmb represents para-methoxy benzyl protecting group and r1 and r2 are alcohol protecting groups. Following cyclization, the resulting compound can be subjected to several chemical trans-formations followed by alkylation, hydrolysis and salt formation to yield treprostinil sodium.
12/12/13
20130331581
1,2,3-triazole containing artemisinin compounds and process for preparation thereof
The present invention relates to 1,2,3-triazole containing artemisinin compounds and process for preparation thereof. Described herein is the synthesis, bioassay results and usefulness of the artemisinin derived compounds resulting from 1,3-di-polar cycloaddition reaction of artemisinin derived azide or alkyne with aliphatic or aromatic diazides.
12/05/13
20130324604
Clog resistant insect control formulations having terminal diyne acetylenic hydrocarbon and pyrethrin
Disclosed are pyrethrin-based insect control compositions which have been formulated to reduce wick clogging. An acetylenic hydrocarbon having at least two terminal alkyne groups, such as 1,8-nonadiyne, together with an antioxidant such as dilauryl thiodipropionate, are used to reduce clogging caused by components of pyrethrum extract..
12/05/13
20130323642
Photoinduced alkyne-azide click reactions
The present invention includes a composition comprising an alkyne-based substrate, an azide-based substrate, a cu(ii) salt and a photoinducible reducing agent. The present invention further includes a method of immobilizing a chemical structure in a given pattern onto a section of the surface of a solid substrate, using the photoinducible cu(i)-catalyzed azide-alkyne cycloaddition click reaction..
11/21/13
20130310580
Method for producing optically active fluorine-containing oxeten
A method for producing an optically active fluorine-containing oxeten, the method being provided to include the steps of causing a fluorine-containing α-ketoester and an internal alkyne to react with each other in the presence of a transition metal complex that has an optically active ligand.. .
11/21/13
20130310570
Methods including latent 1,3-dipole-functional compounds and materials prepared thereby
Methods that include latent 1,3-dipole-functional compounds are disclosed herein. The latent 1,3-dipole-functional compound (e.g., an oxime) can be used to form an active 1,3-dipole-functional compound (e.g., a nitrile oxide) that can be used to react with a cyclic alkyne in a dipolar cycloaddition reaction..
11/07/13
20130296574
Preparation of sensors on oligo- or poly (ethylene glycol) films on silicon surfaces
A sensor that includes a) a silicon (si) substrate having a surface; and b) a monolayer of oligoethylene glycol (oeg) bonded to the surface via silicon-carbon bonds. Regions of the oeg monolayer distal to the surface are functionalized with a molecular probe serving as a recognition element for a bioanalyte.
10/31/13
20130289266
Spiroannulated nucleosides and process for the preparation thereof
We claim a simple strategy for the synthesis of a collection of c(3′)-spirodihydroisobenzo- furannulated and c(3′)-spirodihydroisobenzo-furannulated nucleosides featuring a [2+2+2]-cyclotrimerization as the key reaction. The cyclotrimerization reactions are facile with the unprotected nucleosides having a diyne unit.
10/24/13
20130281656
Methods for labeling a substrate having a plurality of thiol groups attached thereto
Methods for derivatizing the surface of a substrate having a plurality of thiol groups thereon are disclosed herein. The method can include reacting the thiol groups with an o-quinone methide, which can optionally be generated by irradiating an o-quinone methide precursor compound.
10/17/13
20130270443
Scintillator compositions
Wherein r1 and r2, being identical or different, are independently chosen from the group consisting of hydrogen, halogen, alkyl which optionally contains one or more heteroatoms, alkoxy, aryl and alkyne with an aryl end group; r3 is chosen from the group consisting of hydrogen, alkyl which optionally contains one or more heteroatoms, aryl, heterocycle, ether and ester; r4 and r5, being identical or different, are independently chosen from the group consisting of hydrogen, alkyl which optionally contains one or more heteroatoms, aryl, heterocycle, ether and ester, whereby the r4 and r5 groups are optionally combined to one cyclic structure; and r6, if present, is chosen from the group consisting of hydrogen, aryl and alkyl.. .
10/10/13
20130266513
Imaging of meningiomas using phingylbenzothiazole, stilbene, or biphenylalkyne derivatives
Methods for detecting or ruling out a meningioma in a patient using a phenylbenzothiazole derivative or a stilbene derivative or a biphenylalkyne derivative, and a medical imaging technique such as positron emission tomography/computed tomography are disclosed. In one version of the method, the phenylbenzothiazole derivative is a compound of formula (v):.
10/10/13
20130264747
Self-assembly patterning of organic molecules on a surface
The embodiments disclosed herein include all-electron control over a chemical attachment and the subsequent self-assembly of an organic molecule into a well-ordered three-dimensional monolayer on a metal surface. The ordering or assembly of the organic molecule may be through electron excitation.
10/10/13
20130264216
Electrocatalytic alkenes and alkynes dimerizations and trimerizations
The present disclosure relates generally to carbon to carbon coupling processes, and more specifically, to dimerization or trimerization by electrocatalysis of alkenes and alkynes at room temperature.. .
10/03/13
20130261295
Highly active multidentate catalysts for efficient alkyne metathesis
The invention relates to highly active and selective catalysts for alkyne metathesis. In one aspect, the invention includes a multidentate organic ligand wherein one substrate-binding site of the metal center is blocked.
09/26/13
20130247810
Methods for the synthesis of alkyne-containing dicarba bridges in peptides
A method, system and device for facilitating the retrieval of a marine anchor from an underwater obstruction, the device being configured to actuate when subjected to a force load of a predetermined peak force threshold to effect a change in the point of retrieval that an anchor rode makes with the anchor. The obstructed anchor may be retrieved from another direction, such as a direction opposite from which the anchor was set..
09/05/13
20130231473
Oligonucleotide ligation
A method for joining oligonucleotides. The method includes joining together one or more oligonucleotides by reacting an alkyne group lined to an oligonucleotide with an azide group linked to an oligonucleotide to form a triazole linkage.
08/15/13
20130209361
Process for producing radiohalogenated bioconjugates and products thereof
The present invention relates to a new synthetic process in which an alkyne and an azide react to form a radioisotopic bioconjugate construct. The reaction is particularly useful for producing compounds for use in imaging and radiotherapy applications.
07/04/13
20130172642
Palladium-modified hydrotalcites and their use as catalyst precursors
The present invention relates to hydrotalcite-like compounds, wherein pd2+ occupies at least part of the octahedral sites in the brucite-like layers. According to another aspect, the invention is concerned with methods of converting these hydrotalcite-like compounds into materials comprising particles, in particular nanoparticles, of an ordered intermetallic compound of palladium and at least one constituent metal of the palladium-modified hydrotalcites.
06/27/13
20130165683
New route to synthetic analogues of rocaglamide and aglafoline using cascade transformations initiated by oxy-cope rearrangement of bis-alkynes
A method for preparing a cyclobutene compound or a cyclopentenone is provided. The method comprises contacting an α,β-diketone with a metal acetylide at a temperature below 0° c.
06/20/13
20130158031
Alkyne-bridged hetero-aromatics and uses thereof
This invention relates to novel alkyne-bridged hetero-aromatics as described in the specification which are pde10a inhibitors and useful for the treatment of neurological, psychiatric disorder, metabolic disorders, such as schizophrenia, parkinson's disease, huntington's disease, alzheimer's disease, learning memory disorder, drug addiction (abuse), sleeping disorder, depression, obesity, non-insulin dependent diabetes, bipolar disorder, obsessive compulsive disorder, or pain; to process for their preparation; to pharmaceutical compositions comprising them; and to methods of using them.. .
06/13/13
20130150331
Alkyne and alkene derivatives as sphingosine 1-phosphate-1 receptor modulators
The present invention relates to novel alkyne and alkene derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.. .
06/13/13
20130145974
Composition and method for reducing sox and nox emissions from combustion of fuel
A fuel mixture characterized by reduced sox and nox emissions from combustion of the fuel, comprising: fuel; and an ester additive derived from reaction of i) a c6-c16 aliphatic straight chain or branched chain monocarboxylic acid, wherein aliphatic is defined as of or relating to a major group of organic compounds, structured in open or branched chains, including alkanes, e.g. Paraffins, alkenes, e.g.
06/06/13
20130144102
Catalysts for the alkyne metathesis
Organometallic compounds of the general formula (i), in which m=mo, w, are claimed.. .
06/06/13
20130144083
Process and method for the efficient preparation of fullerynes
The preparation of novel fullerynes which are fullerenes (e.g. C60, c70, c80, etc.) that contain one or more alkyne functionalities and may contain additional functional groups such as hydroxyls, halogens, esters, haloesters, phenyl, oligo(ethylene glycol)s, perfluorinated alkyl chains, and the like.
05/30/13
20130137898
Electrochemical co-production of chemicals utilizing a halide salt
The present disclosure includes a system and method for co-producing a first product and a second product. The system may include a first electrochemical cell, at least one second reactor, and an acidification chamber.
05/30/13
20130137861
Novel methods for the synthesis and purification of oligomers
Wherein x is a phosphoramidite group, an h-phosphonate group, an acetal group, or an isocyanate; c is a direct bond or a cleavable adaptor represented by —ca-cb—; l is a hydrocarbyl chain; and h is a terminal alkyne or an activated cyclooctyne. The reagent of formula (a) can be used in the synthesis and purification of oligonucleotides..
05/23/13
20130130337
Enzymatic acylation method using an acylphosphonate donor
The invention relates to an enzymatic acylation method including at least the following steps of: contacting at least one compound having at least one function selected from among the amine, alcohol, or thiol functions, at least one microorganism having an acyl transfer activity and/or an acyl transfer enzyme, and at least one acylphosphonate donor of formula (i), where: r is an alkyl, alkene, uikyne, aryl, or aralkyl radical, or is —ora, —sra, —nrarb, where ra and rb are identical or different and are h, an alkyl, alkene, alkyne, aryl or aralkyl radical, the alkyl, alkene, alkyne, aryl or aralkyl radicals being optionally substituted; x is o or s; y and z, which are identical or different, are —or1, —or2, —sr1, —sr2, —nr′1r″1, —nr′2r″2; r1, r2, r′1, r′2, r″1 and r″2, which are identical or different, are an alkyl, alkene, alkyne, aryl or aralkyl radical, said alkyl, alkene, alkyne, aryl or aralkyl radicals being optionally substituted; and recovering the compound including at least one acyl function, said function being selected from among the amine, alcohol, or thiol functions.. .
05/02/13
20130109855
Modular synthesis of graphene nanoribbons and graphene substructures from oligo-alkynes
A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.. .
04/25/13
20130098273
Cement composition containing a substituted ethoxylated phenol surfactant for use in an oil-contaminated well
A well treatment composition comprises a surfactant comprising a substituted ethoxylated phenol having at least one substituent, 1 to 14 moles of ethylene oxide, and the substituent being an alkyl, alkene, or alkyne with a carbon chain length in the range of 4 to 25, wherein the substituted ethoxylated phenol is selected from the group consisting of: ortho-, para-, or meta-substituted ethoxylated phenol; cardanol ethoxylate; derivatives thereof; and combinations of any of the foregoing. Preferably, the surfactant comprises cardanol ethoxylate, a substituted cardanol ethoxylate, and derivatives thereof.
04/18/13
20130096295
Maltoside and phosphocholine derivatives, uses thereof and methods of preparing artificial lipid structures thereof
Disclosed are saccharide and phosphocholine derivatives. The derivatives include azide and alkyne derivatives which form one end of a variable length carbon chain.
03/28/13
20130079567
Enantiopure base-metal catalysts for asymmetric catalysis and bis(imino)pyridine iron alkyl complexes for catalysis
Disclosed herein are iron, nickel, or cobalt compounds having tridentate ligands, which can have at least one chiral moiety in the molecular structure thereof and the use of these compounds for the hydrogenation and transformation of olefins (preferably prochiral) and alkynes.. .
03/28/13
20130079361
Novel iodo pyrimidine derivatives useful for the treatment of macrophage migration inhibitory factor (mif)-implicated diseases and conditions
Compounds useful for the inhibition of macrophage migration inhibitory factor (mif) are provided herein, having the formula (i): wherein a is selected from the group consisting of aromatic or non-aromatic rings, bicyclic rings, polycyclic rings, alkenes or alkynes; b is h, oh, or, sr, nh2, nhr, or alkyl; r is h or alkyl, and x and y are independently n or ch, but one of x and y must be n. Also provided are pharmaceutical compositions comprising a formula i compound and methods for the treatment of mif-implicated diseases or conditions, comprising administering a safe and effective amount of a formula i compound..
02/21/13
20130046084
Oligonucleotide ligation
Oligonucleotide chemistry is central to the advancement of core technologies such as dna sequencing, forensic and genetic analysis and has impacted greatly on the discipline of molecular biology. Oligonucleotides and their analogues are essential tools in these areas.
02/21/13
20130046083
Oligonucleotide ligation
Oligonucleotide chemistry is central to the advancement of core technologies such as dna sequencing, forensic and genetic analysis and has impacted greatly on the discipline of molecular biology. Oligonucleotides and their analogues are essential tools in these areas.
02/21/13
20130045387
Articles, coating compositions, and methods
There is provided a coating composition comprising nonspherical nanoparticles; spherical nanoparticles; optionally hydrophilic groups and optional an surfactant; and a liquid medium comprising water and no greater than 30 wt % organic solvent, if present, based on the total weight of liquid medium, where at least a portion of the nonspherical nanoparticles or at least a portion of the spherical nanoparticles comprises functional groups attached to their surface through chemical bonds, wherein the functional groups comprise at least one group selected from the group consisting of epoxy group, amine group, hydroxyl, olefin, alkyne, (meth) acrylato, mercapto group, or combinations thereof. There is also provided a method for modifying a substrate surface using the coating composition and articles made therefrom..
02/07/13
20130035322
Gold complexes
Gold (i) hydroxide complexes of the form z-au-oh and digold complexes of the form z—au-(μoh)—au—z where groups z are two electron donors are provided. The groups z may be carbenes, for example nitrogen containing heterocyclic carbenes (nhcs), phosphines or phosphites.
01/31/13
20130030170
Enantioselective cyclopropenation of alkynes
The cobalt(ii) complex of new d2-symmetric chiral porphyrin 3,5-dimes-chenphyrin, [co(p2)], has been shown to be a highly effective chiral metalloradical catalyst for enantioselective cyclopropenation of alkynes with acceptor/acceptor-substituted diazo reagents such as α-cyanodiazoacetamides and α-cyanodiazoacetates. The [co(p2)]-mediated metalloradical cyclopropenation is suitable to a wide range of terminal aromatic and related conjugated alkynes with varied steric and electronic properties, providing the corresponding tri-substituted cyclopropenes in high yields with excellent enantiocontrol of the all-carbon quaternary stereogenic centers.
01/31/13
20130029981
Compounds, compositions, and methods for controlling biofilms
The invention relates to substituted 2-aminoimidazoles and their imidazo[1,2-a]pyrimidinium salts precursors being active against biofilm formation. The invention also relates to imidazo[1,2-a]pyrimidinium salts bearing an azidoalkyl substituent, and to substituted 2-aminoimidazoles wherein the amino group bears a terminal heterocyclic group such as a triazolyl group which are formed through azide-alkyne huisgen cycloaddition starting from said imidazo[1,2-a]pyrimidinium salts bearing an azidoalkyl substituent.
01/24/13
20130023018
Method for producing acyloxypyranone compound, method for producing alkyne compound, and method for producing dihydrofuran compound
An acylating agent and a hydrolase are caused to act on a hydroxypyranone represented by formula (i) in a water-containing organic solvent, to thereby produce an acyloxypyranone compound represented by formula (ii) (wherein r1 represents an acyl group). Then, an acetylene organic metal compound represented by formula (iii) (wherein r2 represents a hydrogen atom or a tri-substituted silyl group, and m represents an alkali metal atom, aluminum, or a magnesium monohalide) and a coordinating additive are caused to act on the acyloxypyranone compound represented by formula (ii), to thereby produce an alkyne compound represented by formula (iv).
01/24/13
20130022785
Oligosaccharide/silicon-containing block copolymers for lithography applications
The present invention discloses diblock copolymer systems that self-assemble to produce very small structures. These co-polymers consist of one block that contains silicon and another block comprised of an oligosaccharide that are coupled by azide-alkyne cycloaddition..
01/10/13
20130012673
Curable fluoroelastomer compositions
This invention relates to curable fluoroelastomer compositions comprising a) fluoroelastomers having either nitrile, alkyne or azide cure sites and b) fluorinated curatives containing diazide, dinitrile or dialkyne groups for reacting with cure sites on the fluoroelastomer. Fluoroelastomers having azide cure sites form crosslinks with curatives having dinitrile or dialkyne groups.


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Alkyne topics: Small Molecule Library, Electrocatalytic, Organic Molecules, Disassembly, Organic Molecule, Tomography, Positron Emission Tomography, Computed Tomography, Meningioma, Robustness, Obstruction, Oligonucleotide, Nucleotide, Radiotherapy, Metallic Compound

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