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Alkyne

Alkyne-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Triazabutadienes as cleavable cross-linkers
The Arizona Board Of Regents On Behalf Of The University Of Arizona
November 09, 2017 - N°20170320834

Triazabutadiene molecules as cleavable cross-linkers adapted to cross-link components with dick chemistry, e. G., clickable triazabutadienes. For example, in some embodiments, the triazabutadienes feature alkyne handles attached to the imidazole portion or the aryl portion of the triazabutadienes, wherein the alkyne handles can link to azide handles (e. G., azide handles disposed on other components) via dick chemistry. Also described ...
Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds
University Of Georgia Research Foundation, Inc.
November 09, 2017 - N°20170320815

1,3-dipole-functional compounds (e. G., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e. G., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a ...
Method of hydrosilylation implementing an organic catalyst derived from germylene
University Of Georgia Research Foundation, Inc.
November 02, 2017 - N°20170313729

The present invention concerns a method for the hydrosilylation of an unsaturated compound comprising at least one ketone function, one aldehyde function, one alkene function and/or one alkyne function, with a compound comprising at least one hydrogen-silyl function implementing an organic catalyst of tri-coordinated germanium.
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Photochemical modification of a solid surface
University Of Georgia Research Foundation, Inc.
October 19, 2017 - N°20170297018

A process for the modification of a solid material, said process comprising contacting a surface of the solid material comprising nucleophilic groups with a hydrosilane in a first step to produce a hydrosilanized surface, and contacting said hydrosilanized surface with at least one alkene and/or alkyne under irradiation with visible and/or ultraviolet light in a second step.
Cu(i)-catalyzed azide-alkyne cycloadditions (cuaac) ligands and methods for carrying out cu(i)-catalyzed ...
University Of Georgia Research Foundation, Inc.
October 19, 2017 - N°20170297008

A cu(i)-catalyzed azide-alkyne cycloadditions (cuaac) ligand comprising: a catalytic core; a fluorous tag; and a linker binding the fluorous tag to the catalytic core. A method for carrying out a cu(i)-catalyzed azide-alkyne cycloaddition reaction, comprising: combining in a solution an alkyne-tagged component, an azide-tagged component and a cu(i)-catalyzed azide-alkyne cycloadditions (cuaac) ligand comprising: a ...
Cellulose ethers substituted with hydroxyl and alkyne groups and with hydroxyalkyl, alkyne and azide groups, ...
Se Tylose Gmbh & Co. Kg
September 07, 2017 - N°20170253674

Nonionic, water-soluble cellulose ethers are disclosed with hydroxyalkyl groups and ω-alkynyl groups, each joined to the cellulose via an ether bond, the degree of molar substitution ms(alkyne) being in the range from 0. 001 to 0. 30. The cellulose ethers may further contain azido groups, preferably 3-azido-2-hydroxypropyl groups, likewise joined to the cellulose by an ether bond, the ms(ahp) ...
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Inorganic filler, resin composition comprising the same and heat radiation substrate using the same
Lg Innotek Co., Ltd.
August 17, 2017 - N°20170233554

An inorganic filler according to an embodiment of the present invention includes a boron nitride agglomerate and a coating layer formed on the boron nitride agglomerate and including a —si—r—nh2 group, and r is selected from the group consisting of an alkyl group having 1 to 3 carbon atoms, an alkene group having 2 to 3 carbon atoms, and ...
Covalently cross linked hydrogels and methods of making and using same
The Regents Of The University Of Colorado, A Body Corporate
August 17, 2017 - N°20170232143

A thiol-yne polymeric material and methods for producing said polymers are disclosed. The material is produced by the radically mediated polymerization of monomers having alkyne and thiol functional groups. The alkyne moiety, internal or terminal, may react with one or two thiols. Degradable monomers may be used to form degradable polymers.
Platinum-catalyzed silicone drug delivery devices and methods of use thereof
International Partnership For Microbicides, Inc.
August 10, 2017 - N°20170224823

The present invention provides intravaginal drug delivery devices, such as intravaginal rings, comprising active pharmaceutical ingredients (apis) having terminal alkene, alkyne or carbonyl functionalities. The devices of the invention exhibit increased recovery of the active pharmaceutical ingredient from platinum-catalyzed silicone polymers due to the optimization of drug particle size and cure conditions. The present invention also provides methods of preventing ...
Uncharged pyrenyloxy sulfonamide dyes for conjugation with biomolecules
International Partnership For Microbicides, Inc.
July 27, 2017 - N°20170210904

Wherein r1 is a leash joined to the pyrenyloxy group via an ether link containing generally a reactive functional group such as, activated carbonate, activated ester, amino group, azide or alkyne for conjugation with biomolecules; r2 and r3 are hydrogen atoms, or short alkyl chains, or cyclic rings with or without heteroatoms such as nitrogen, oxygen, sulfur, phosphorus. The spectral ...
Treatment of meningiomas using phenylbenzothiazole, stilbene, biphenylalkyne, or pyridine derivitives
Mayo Foundation For Medical Education And Research
July 13, 2017 - N°20170196999

A method and composition for treating a meningioma in a subject are disclosed. The method includes the step of administering to the subject a therapeutically effective amount of a composition including a cytotoxic agent associated with a phenylbenzothiazole derivative or a stilbene derivative or a biphenylalkyne derivative that accumulates within meningiomas. In one version of the method, the phenylbenzothiazole derivative ...
Heterocyclylalkyne derivatives and their use as modulators of mglur5 receptors
Mayo Foundation For Medical Education And Research
June 29, 2017 - N°20170182011

Their use as allosteric modulators of mglur5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction, such as schizophrenia or cognitive decline, dementia or cognitive impairment, or other pathologies that can be related directly or indirectly to glutamate dysfunction.
Polyurethane materials formed from unsaturated plant oils via an alkyne zipper reaction
International Business Machines Corporation
June 15, 2017 - N°20170166680

A process of forming a polyurethane material includes forming an alkyne-terminated triglyceride material from an unsaturated plant oil. The process also includes forming a hydroxyl-terminated polyol material from the alkyne-terminated triglyceride material. The process further includes polymerizing a mixture that includes the hydroxyl-terminated polyol material to form a polyurethane material.
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Engineered co2-fixing chemotrophic microorganisms producing carbon-based products and methods of using the same
Kiverdi, Inc.
June 01, 2017 - N°20170152533

Disclosed herein are microorganisms containing exogenous or heterologous nucleic acid sequences, wherein the microorganisms are capable of growing on gaseous carbon dioxide, gaseous hydrogen, syngas, or combinations thereof. In some embodiments the microorganisms are chemotrophic bacteria that produce or secrete at least 10% of lipid by weight. Also disclosed are methods of fixing gaseous carbon into organic carbon molecules useful for ...
Toxic rna inhibitors self-assembled in situ
Kiverdi, Inc.
May 25, 2017 - N°20170143703

Potent modulators of rna function can be assembled in cellulo by using the cell as a reaction vessel and a disease-causing rna as a catalyst. When designing small molecule effectors of function, a balance between permeability and potency must be struck. Low molecular weight compounds are more permeable while higher molecular weight compounds are more potent. The advantages of both ...
Tetracenothiophene derivatives with alkoxy-c-alkyne solubilising units and their applications as organic semiconductors
Sumitomo Chemical Company Limited
May 11, 2017 - N°20170133605

Tetracenothiophene derivatives are disclosed, which comprise alkoxy-c-alkyne solubilising groups at transversal positions of the tetracenothiophene unit. These compounds enable preferential molecular stacking and a high field effect mobility and at the same time show improved solubility as compared to known benzothiophene- and pentacene-based materials. In addition, organic thin films comprising these derivatives, their use in electronic devices and components, such ...
Secondary battery
Sumitomo Chemical Company Limited
April 27, 2017 - N°20170117577

Where r5 and r6 are selected from the group consisting of a hydrogen group, an alkyl group, an alkyne group, and an aryl group.
Platinum(iv) compounds and methods of making and using same
University Of Georgia Research Foundation, Inc.
April 06, 2017 - N°20170096443

Reactions of 1,3-dipole-functional (e. G., azide-functional) platinum(iv) compounds with cyclic alkynes under conditions effective for a cycloaddition reaction to form a heterocyclic compound are disclosed herein. In certain embodiments, the conditions effective for the cycloaddition reaction to form the heterocyclic compound includes the substantial absence of added catalyst (e. G., copper catalyst).
Base-catalyzed silylation of terminal alkyne c-h bonds
California Institute Of Technology
March 30, 2017 - N°20170088563

The present invention is directed to a mild, efficient, and general direct c(sp)-h bond silylation. Various embodiments includes methods, each method comprising or consisting essentially of contacting at least one organic substrate comprising a terminal alkynyl c—h bond, with a mixture of at least one organosilane and an alkali metal hydroxide, alkali metal alkoxide, or alkali ...
Sydnone derivatives for conjugation of compounds of interest
Commissariat A L'energie Atomique Et Aux Energies Alternatives
March 23, 2017 - N°20170081300

The present invention relates to a process for the preparation of a first compound of interest c1 functionalized with a sydnone compound and to the corresponding functionalized c1 compound of interest. The present invention also relates to a process for the preparation of a conjugate of two compounds of interest c1 and c2 implying a sydnone compound and to the ...
Composition for manufacturing semiconductor device and method of manufacturing semiconductor device using the composition
Samsung Electronics Co., Ltd.
March 02, 2017 - N°20170062217

A composition for manufacturing a semiconductor device includes at least one carbon-based compound that includes at least one of an alkyne group and an azide group, and a solvent. A method of manufacturing a semiconductor device includes forming a feature layer on a substrate, coating the feature layer with a composition including alkyne and azide, forming a carbon-containing layer including ...
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