|| List of recent Agitation-related patents
| Production of polyamides by polycondensation|
In a process for producing polyamides by polycondensation of polycondensable polyamide-forming monomers and/or oligomers in reaction mixtures comprising same, which may be water-containing but are free from organic solvents, the polycondensation is effected in an agitated reactor under agitation in a first step in the liquid phase and after a phase change taking place during the process in the same reactor is effected in a subsequent second step in the solid state, wherein the temperature in the reactor is below the melting point of the polyamide in the second step at least.. .
| Rotary slide stainer|
A slide stainer and a method for operating the slide carrier is disclosed. The slide stainer includes a slide carrier that carries one or more laboratory slides; a vessel that is capable of carrying fluid for staining the laboratory slides and that is sized to accommodate the laboratory slides; a slide transporter that moves the slide carrier into and out of the vessel; and a spring loaded pin that engages with a surface of the slide stainer to limit free-fall translation of the slide carrier in an event of a power loss.
| Solvent-free process for obtaining phospholipids and neutral enriched krill oils|
The invention discloses a new solvent-free process for obtaining phospholipids and neutral lipids enriched krill oils containing dha and epa poly-unsaturated fatty acids and astaxanthin. The process includes cooking fresh krill at high temperature—without agitation and or grinding; decanting the cooked krill for obtaining a partial de-fatted and de-watered solid and a liquid; squeezing the obtained solid to obtain a press liquid and a solid fraction; centrifuging the press liquid to obtain the phospholipids enriched krill oil; centrifuging of the decanter liquid obtained to obtain the neutral lipid enriched krill oil and stickwater..
| Image forming apparatus and image forming method|
This invention is to provide a technique of always obtaining a stable output image in image formation using toner. A supplier (1217) supplies toner in a decided toner supply amount.
| Sample processing apparatus and sample processing method|
A sample processing apparatus comprising a controller; an agitating section configured to agitate a sample in a sample tube; and a processing section configured to process the agitated sample, wherein the controller is configured to control the agitating section to agitate a sample in a first type of sample tube under a first agitation condition, and to control the agitating section to agitate a sample in a second type of sample tube, which contains a sample of lower volume than the first type of sample tube, under a second agitation condition different from the first agitation condition.. .
| Method and apparatus for contact refrigeration in cryogenic solid belt freezer|
Methods and apparatus for contact freezing a food product. A conveyor belt or other support may have an active region that supports materials on an outer surface.
|Microfluidic agitator devices and methods for agitation of a fluid|
According to various embodiments, a microfluidic agitator device may be provided. The microfluidic agitator device may include: an air inlet; an air outlet; an elastic diaphragm provided between the air inlet and the air outlet and configured to oscillate if an airflow from the air inlet to the air outlet is provided; and a chamber coupled to the elastic diaphragm..
|Method of processing a bituminous feed using agglomeration in a pipeline|
The present disclosure relates to a method of processing a bituminous feed. The bituminous feed is contacted with an extraction liquor to form a slurry.
|Herbal/plant sifter apparatus and method|
A plant/herb sifting apparatus and method is disclosed. The apparatus comprises a containment unit having at least two levels of a sifting means; the containment unit comprising a primary containment, a secondary containment and a collection base to sift and refine a plant/herb component by a vibrating and agitation means.
|Liquid supply method|
A liquid ejecting apparatus comprising a liquid storage unit that stores a liquid; a tank having a liquid capacity greater than that of the liquid storage unit; a liquid supply unit supplying the liquid in the liquid storage unit to the tank; an agitation device that agitates the liquid accommodated in the tank; and a liquid ejection unit that ejects the liquid from the tank.. .
|Nanostructured titania semiconductor material and its production process|
A nanostructured titania semiconductor material termed tsg-imp having a predetermined crystal size is produced by a sol-gel method by adding a titanium alkoxide to an alcoholic solution, adding an acid to the alcoholic solution, subjecting the acidic solution to agitation under reflux conditions: stabilizing the medium and adding bidistilled water under reflux until gelation; subjecting the gel to aging until complete formation of the titania which is dried and calcined.. .
|Healthcare facility disinfecting system|
A system and process for disinfecting rooms such as health care facility rooms with an oxygen/ozone mixture is described, which is effective to combat “superbugs” such as clostridium difficile (c. Difficile); e.
|Encryption processing device and method|
An encryption processing device includes: a memory configured to store a first secret key and a first agitation value operated with the first secret key; and a processor coupled to the memory and configured to: receive a first random number, generate a second agitation key based on the first secret key and the first agitation value, generate a first encryption information based on the second secret key and the first random number, update the first agitation value stored in the memory, and output the first agitation value and the first encryption information.. .
|Pressing a weld using the friction agitation welding process for better surface adjustment|
A friction agitation welding process for the joining of abutting plate-shaped workpieces consisting of an aluminium alloy, wherein a rotating bobbin tool is moved along a weld between the two plate-shaped workpieces during feed, exerting a first and a second contact pressing force on first and second sides, respectively, and wherein said bobbin tool is subjected to an additional axial force during its movement along the weld to plastically deform the area of the created welding seam such that the welding seam is pressed towards one side of the plate-shaped workpieces while forming a welding seam elevation protruding opposite from the workpiece surface.. .
|Method of processing a bituminous feed using an emulsion|
The present disclosure relates to a method of processing a bituminous feed. The bituminous feed is contacted with a bridging liquid-in-extraction liquor emulsion to form a slurry.
|Obstruction clearing assembly|
An obstruction clearing assembly for clearing an obstruction from a plumbing fixture and the respective pipe. The assembly positions inside the fixture, and is accessible and controlled from outside the fixture by a handle.
|Gravity assisted compost reactor|
A composting system is provided that uses gravity and natural thermal convection to yield a compact, modular, plug-flow compost reactor requiring minimal aeration and agitation energy. The compost reaction takes place in a self-supporting containment unit which is mounted at an angle with respect to its supporting base pad such that minimal external energy is required to mix and transport the composting material during its residence time within the container.
|Developing device and image forming apparatus including the same|
A developing device and an image forming apparatus including the same includes an agitating and conveying unit that receives a developer, and at least one agitating and conveying member to mix and agitate the developer and convey the developer in a developer conveying direction. A developing roller faces a photosensitive drum on which an electrostatic latent image is formed, and attaches the developer to an outer surface of the developing roller.
|Developer storage container and manufacturing method thereof|
In order to achieve an improvement in terms of workability when mounting a developer agitation member and a drive transmission member to a container portion storing developer, there is provided a method of mounting a developer storage container in which, when mounting a developer agitation member to a developer storage portion, a drive transmission member is inserted for connection from an end portion of the developer agitation member, the developer agitation member exhibits a first phase and a second phase. The first phase allows connection of the developer agitation member and the drive transmission member in the insertion path of the drive transmission member, whereas the second phase does not allow connection of the developer agitation member and the drive transmission member in the insertion path of a support member..
|Vortex device for separating cold gas and hot gas|
A vortex type cold and hot gas separating device (100) includes a body (110) having a cylindrical inner wall surface (111), the inner wall surface (111) defining a cylindrical inner chamber (112) having a first end (113) and a second end (114); an intake and agitation fan device (120) attached to the body (110) at the first end (113) which sucks external gas into the cylindrical inner chamber (112) and agitates the external gas to form a first vortex traveling towards the second end (114); a hot gas stream discharge port (130) located at or adjacent to an edge of the second end (114) to discharge a part of gas of the first vortex traveling to the hot gas stream discharge port (130) out of the cylindrical inner chamber (112); a vortex return device (140) located at the second end (114) to return the remaining gas of the first vortex which is not discharged from the hot gas stream discharge port (130), thereby forming a second vortex traveling towards the first end (113) of the cylindrical inner chamber (112) through a cyclone core of the first vortex; and a cold gas stream discharge port (150) located at a radial center of the first end (112) of the cylindrical inner chamber or located adjacent to and around the radial center. A temperature of the gas discharged from the hot gas stream discharge port (130) is higher than a temperature of the gas discharged from the cold gas stream discharge port (150)..
|Image forming apparatus|
An image forming apparatus configured to form an image on a recording medium, includes a developer container configured to store developer, an image bearing member configured to be rotated and on which a latent image is formed, a developer bearing member configured to bear developer and to be rotated to develop the latent image, an agitation member configured to be rotated to agitate the developer stored in the developer container, and a control unit configured to control the rotations of the image bearing member, the developer bearing member, and the agitation member so as to rotate the agitation member while the image bearing member is not rotated.. .
|Automated systems and methods for preparing biological specimens for examination|
The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids.
|Developer storage body, image forming unit and image forming apparatus|
A developer storage body includes a storage portion for storing a developer, an agitation member for agitating the developer stored in the storage portion, and a swing member that swings in the storage portion by contact with the agitation member. A contact portion is provided at a first end portion of the swing member.
|Reaction apparatus and method using supercritical water or subcritical water|
At least two inlet flow paths for flowing the raw material fluid and the supercritical water or subcritical water into the mixing flow path are provided, along with an agitation blade having a rotating shaft set on a center shaft of the mixing flow path and an agitation blade having a rotating shaft set on a center shaft of the mixing flow path.. .
|Apparatus for fluid processing a workpiece|
A method of fluid processing a semiconductor workpiece, including disposing a workpiece holder with a housing capable of containing a fluid, the workpiece holder retaining the workpiece, providing an agitation system connected to the housing and comprising a member disposed within the housing adjacent the workpiece holder, and agitating the fluid by moving the member substantially parallel to a surface of the workpiece with a non-uniform oscillatory motion, the non-uniform oscillatory motion being a series of substantially continuous geometrically asymmetric oscillations wherein each consecutive oscillation of the series is geometrically asymmetric having at least two substantially continuous opposing strokes wherein reversal positions of each substantially continuous stroke of the substantially continuous asymmetric oscillation are disposed asymmetrically with respect to a center point of each immediately preceding substantially continuous stroke of the oscillation.. .
|Rotary agitation type heat treatment apparatus|
A rotary agitation type heat treatment apparatus includes: a cylindrical member for performing heat treatment on a material to be treated supplied inside the cylindrical member from one end thereof; a rotating unit for rotating the cylindrical member; a heating unit for heating the material supplied inside the cylindrical member; and agitation members arranged in the cylindrical member. Each agitation member has a shaft structure and two or more blades provided on the shaft structure.
|Compositions and methods comprising energy absorbing materials for follicular delivery|
The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g.
|Storage-stable formulation of paracetamol in aqueous solution|
The present invention relates to a method for the production of a formulation that is stable to oxidation and that is based on paracetamol in an aqueous solvent, comprising the steps of (i) dissolving paracetamol in an aqueous solvent comprising an isotonic agent that is sodium chloride and a buffer agent that is sodium citrate, having a temperature between 65° c. And 95° c.
|Compositions and methods comprising energy absorbing compoundfs for follicular delivery|
The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g.
A device for detecting an analyte in a sample, which includes a radiation source adapted to generate electromagnetic radiation; a transducer capable of transducing a change in energy to an electrical signal; at least one tethered reagent on or proximal to the transducer, the tethered reagent having a binding site which is capable of binding the analyte; a chamber for holding the sample in fluid contact with transducer, wherein the chamber is adapted to contain the sample on inversion, partial inversion or agitation of the device; and a detector which is capable of detecting the electrical signal generated by the transducer.. .
An ice agitation system includes an adaptor and an ice agitator. The adaptor includes a disk portion and an auger mounting channel.
|Infrared video tracking for use in projecting onto dynamic water features|
A projection system for projecting a still or video image onto a liquid surface. The system includes an agitation mechanism selectively operable to generate gas bubbles on the liquid surface.
|Integrated ice and beverage dispenser|
An automated ice dispenser (30) decouples the action of agitating ice stored in an ice bin (69) and the action of dispensing the ice and, additionally, uses a controlled action to dispense the ice. Agitation is achieved with a horizontally mounted agitator (91).
|Touch-free medical instrument sanitation station and method thereof|
A cleansing unit for enhanced sanitation compliance and for eradicating a healthcare facility-hosted opportunistic infections, the unit comprising: a hands-free automatic dispenser of disinfectant agent that dispenses such agent either directly on at least one agitation membrane support post having a condom-like mounted textured sheath or directly on the auscultation portion of the stethoscope, said textured sheath designed to provide a frictional agitation of an auscultation portion of a stethoscope to effectively clean and sanitize the stethoscope, and method thereof.. .
|Method for producing alpha-olefin unsaturated dimer|
A method for producing an unsaturated dimer by reacting an α-olefin having 6 to 14 carbon atoms in an agitated vessel, wherein a metallocene-based catalyst is used as a reaction catalyst; and the supply flow rate of hydrogen (vh) to the vessel is 0.2 to 1.2 [(nl/hr) per l of olefin] and the agitation power (pv) is 0.18 kw/m3 or more of the time of reaction.. .
|Device and process for continuous phosgenation|
A continuous process for generation of phosgene from co and cl2 and consumption of the phosgene thus generated in a liquid-phase reaction so as to form organic products p. The process is implemented in two successive reactors r1 and r2, the first reactor r1 being a reactor for catalytic synthesis of phosgene from co and cl2 gas, and the second reactor r2 being a piston reactor, the second reactor r2 being equipped with a mechanical axial agitation device..
|Mixing apparatus for mixing bonding adhesive at die bonder before dispense|
A moveable dispenser assembly including is shown. The dispenser includes a reservoir having bonding adhesive therein including particles and a liquid carrier.
|Low cost backside illuminated cmos image sensor package with high integration|
This invention discloses a backside illuminated image sensor without the need to involve a mechanical grinding process or a chemical-mechanical planarization process in fabrication, and a fabricating method thereof. In one embodiment, an image sensor comprises a semiconductor substrate, a plurality of light sensing elements in the semiconductor substrate, and a cavity formed in the semiconductor substrate.
|Synthesis of highly fluorescent gsh-cdte nanoparticles (quantum dots)|
The invention relates to a method for the synthesis of glutathione-capped cadmium-telluride (gsh-cdte) quantum dots in an aqueous medium, including the steps of: a) preparing a precursor solution of cadmium in a citrate buffer; b) adding glutathione (gsh) to the preceding mixture via strong agitation; c) adding a telluride (potassium or sodium telluride) oxyanion as a telluride donor to the preceding mixture; d) allowing the preceding mixture to react; and e) stopping the reaction by incubation at low temperature.. .
|Substrate cleaning system using stabilized fluid solutions|
A substrate cleaning systems are provided. One system includes a proximity head system for applying a meniscus to a surface of a substrate during a cleaning operation.
|Vacuum cleaner with blower and flexible head for improved particulate removal|
A vacuum cleaner with a flexible head portion and combined suction and blowing mechanism to agitate debris. An external pressured air source is used to provide a source of pressured air for the blowing mechanism.
|Non-invasive reperfusion system by deformation of remote, superficial arteries at a frequency much greater than the pulse rate|
Preferred systems for assisting clearance of an acutely thrombosed artery substantially surrounded by boney external body surfaces which are resistant to deformative displacement relative to the thrombosed artery by the application of external percussive force are described. The method consists of applying targeted, localized, non-invasive, high infrasonic to low sonic frequency vibratory percussion with a serial impact frequency much greater than the pulse rate of a patient being treated, the percussion directed towards a remote, preferably superficial “target vessel” residing palpably close to the skin surface.
|Oral care compositions with improved rheology|
Topical compositions containing from about 40% to about 77% by weight of the composition of a humectant component, said component containing from about 0.25% to about 7% of a structuring humectant selected from polyethylene glycols having an average molecular weight of from about 3,000 to about 8,000, and mixtures thereof; and at least one secondary humectant; the topical composition further comprises abrasive from about 5% to about 35%; from about 0% to about 1.5% of a viscosity modifier; a total solids content of 50% or less; water from about 5% to about 12%; and wherein the structuring humectant is added to the composition in solution with solvent or is added in a controlled manner as a molten material to the composition at a temperature less than about 35° c. And with turbulent mixing or vigorous agitation..
|Process for producing monodisperse polystyrene micro-particles|
A process for producing highly monodisperse polystyrene particles includes steps of mixing water and styrene in a reactor, optionally adding an electrolyte to the mixture, purging the mixture of oxygen, adding a polymerization initiator while agitating and heating the mixture, and maintaining agitation and heating for a time sufficient to achieve a desired yield of monodisperse polystyrene particles having a particle size from 0.25 microns to 2.5 microns and a statistical quality factor greater than 10.. .
|Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions|
The present invention provides novel formulations which mitigate agitation-induced aggregation of immunogenic compositions particularly those having polysaccharide-protein conjugates. Specifically, the novel formulations comprise a poloxamer within a molecular weight range of 1100 to 17,400 which provides significant advantages over previously used surfactants including polysorbate 80.
|Ice agitation and dispensing device and method|
An ice dispensing system includes a rotatable barrel having an opening; an input chute having a first end coupled to an ice making machine and a second end in communication with the opening when the barrel is in a first position; an output chute in communication with the opening when the barrel is in a second position; a containment system positioned around a portion of the body of the barrel; and a drive system coupled to the barrel for rotating the barrel. The opening has a geometry and size that directs the ice and captures a regulated amount of the ice during rotation between the first position and the second position.
|Apparatus and method for detecting gases conveyed by drilling fluids from subterranean wells|
This application describes apparatus and methods for detecting gas content and compositions in drilling fluids while drilling a subterranean well. More specifically, the apparatus includes an agitated drilling fluid trap incorporating an inertial bypass filter and analyzer to rapidly extract and analyze gases liberated from a drilling fluid sample.
|Heparain-bulking agent compositions and methods thereof|
A free-flowing anti-coagulant powder composition, the anti-coagulant composition containing heparin and a bulking agent that is lyophilized or spray dried and ground into a powder. The powdered anti-coagulant composition can be dry filled into syringes and other blood collections systems for rapid dissolution and mixing with collected blood sample without agitation of the container.
|Method for producing high-purity barium chloride with low strontium and high-purity barium chloride with low strontium|
High-purity barium chloride (99.60% or more) is produced having low strontium (lower than 10 ppm) by using barium carbonate or a clear barium chloride filtration and hydrochloric acid mixed under agitation at a maintained temperature and ph. The barium chloride is obtained as liquid phase and then crystallized through further processes..
|Fixative and staining solutions|
The formulations, systems, and methods disclosed herein permit automated preparation of specimens (e.g., biological specimens) for examination. The disclosed formulations, systems, and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids.
|Electro-depositing metal layers of uniform thickness|
The invention is an apparatus and method for forming highly uniform layers of metal on a substrate by electro-deposition. The substrate is electroplated in a bath composed of a quiescent (i.e., no external agitation) electrolyte solution using an effective constant current density carefully selected to match the chemical composition of the electrolyte..
|Foaming juice compositions|
The present invention relates to a simple foaming juice composition with a viscosity, clarity or color of the original juice. In one aspect, the invention relates to a foaming juice composition of a juice product and a food grade ester alginate in an amount sufficient to generate or produce a layer of foam thereon without the addition of other foaming agents when the juice product is subjected to agitation without also producing a significant change in viscosity, clarity or color of the juice product.
|Foaming tea compositions|
The present invention relates to a simple foaming tea composition with a viscosity, clarity or color of the original tea. In one aspect, the invention relates to a foaming tea composition comprising a tea product, a food grade ester alginate, wherein the addition of ester alginate generates or produces a layer of foam upon the tea product when subjected to agitation without also producing a significant change in viscosity, clarity or color of the tea product.
|Method and purge apparatus for preventing deformation of chamber of gas turbine, and gas turbine providing purge apparatus|
In this method of preventing deformation in a turbine casing of a gas turbine, in a turbine casing 10 there is arranged a buffer tank 30. In this buffer tank 30 there are formed a stagnation part agitation air opening 52 which ejects part of the air from an air compressor 21 as stagnation part agitation air ga2 toward a stagnation part 19 within the turbine casing, and an overall agitation air opening 51 which ejects overall agitation air ga1 for agitating gas held in an upper space within the turbine casing.
|Pretreatment of biomass using thermo mechanical methods before gasification|
An integrated plant generates syngas from biomass, where the integrated plant includes a thermo mechanical pulping (tmp) process, a biomass gasifier, a methanol synthesis process, and a liquid fuel generation process. Biomass is received as a feedstock in the tmp process.
|Process for decomposing lignin in biomass|
A mild inexpensive process for treating lignocellulosic biomass involves oxidative delignification of wood using an aqueous solution prepared by dissolving a catalytic amount of manganese (iii) acetate into water and adding hydrogen peroxide. Within 4 days and without agitation, the solution was used to convert poplar wood sections into a fine powder-like delignified, cellulose rich materials that included individual wood cells..
|Encapsulated solid hydrophilic particles|
A process of forming microcapsules is described. The microcapsule population is formed by providing an anionic or cationic, solid hydrophilic core material; providing an oil continuous phase, the oil continuous phase comprising one or more esters with chain length up to about 18 carbons.
|Automated apparatus and method of cell culture|
The invention provides an automated apparatus of cell culture having tanks of culture medium, of growth factors and of cells to be cultured, an incubator having a thermostated enclosure which houses a cell culture vessel, and control computer system. A supporting and agitation device of the culture vessel is provided in the enclosure, and the culture vessel is formed by a bag having at least one inlet port connected to the tanks and one outlet port connected devices for harvesting and storage of the cells after culture, these harvesting and storage devices and tanks being located outside the enclosure and being connected to the cell expansion bag ports by conduits which together with the cell expansion bag form a preassembled module passing through a wall of the enclosure..
|Method of operation of fermentation of carbon monoxide and hydrogen containing gaseous substrate|
A method of gaseous substrate fermentation comprising: adding gaseous substrate comprising carbon monoxide (co) and hydrogen (h2) into an aqueous medium in a bioreactor; said method comprising measuring conversion of co; measuring conversion of h2; increasing flow of gaseous substrate by a preselected flow factor; wherein agitation comprises greater than or equal to target agitation rate.. .
|Apparatus for treating material comprising pressure vessel with drum rotatable arranged inside|
A pressure vessel and a drum rotatably arranged inside which has an inner space for material that is introduced into the pressure vessel. In various embodiments, a drive mechanism rotates the drum in relation to the pressure vessel.
|Pill preparation, storage, and deployment system for wellbore drilling and completion|
Systems and methods for preparation, storage, and/or deployment of a specialized fluid are disclosed. A system for preparation, storage, and/or deployment of a specialized fluid comprises a fluid vessel, a first, second, and third agitation unit, wherein each of the agitation units is at least partially disposed within the fluid vessel, a first, second, and third motor coupled to each of the agitation units, respectively, wherein each of the motors are independently operable.
|Method for cell expansion|
The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor.
|Method and apparatus for mixing, transporting, storing, and transferring thixotropic fluids in one container|
A method for mixing, transporting, storing, and transferring a thixotropic fluid is disclosed. The method includes mixing a thixotropic fluid.
|Methods for producing liquid detergent products|
Disclosed herein are methods for producing liquid detergent products using a vessel comprising an inlet, an outlet, an agitation device, and an additive mixing zone disposed between the inlet and the outlet. The method comprises introducing an unstructured liquid detergent precursor into the inlet of the vessel; mixing an additive and the unstructured liquid detergent precursor in an additive mixing zone to form a combined additive detergent; adding a structurant to the combined additive detergent downstream of the additive mixing zone to form a liquid detergent product.
|Agitation kit and recording apparatus|
An agitation kit includes an information-written medium and a liquid container. The liquid container contains a dispersion medium and settleable particles.
|Nail polish display device|
A nail polish display system includes a case, which may take the form of a shelving system or platform, sized to hold and display multiple bottles of nail polish. The bottles are placed on rollers, vibration generating pads, or placed in vicinity of a magnetic disc or rod.
|Complex alloy electroplating method|
One embodiment is for the close agitation of electroplating solution substantially near an electrode in an electroplating cell. The agitation occurs within the nernst diffusion layer allowing for ion replenishment of the electroplating solution at the working electrode face.
|Methods for expression and purification of immunotoxins|
The present invention relates to a method of expressing an immunotoxin in pichia pastoris strain mutated to toxin resistance comprising a) growing the pichia pastoris in a growth medium comprising an enzymatic digest of protein and yeast extract and maintaining a dissolved oxygen concentration at 40% and above; and b) performing methanol induction with a limited methanol feed of 0.5-0.75 ml/min/io l of initial volume during induction along with a continuous infusion of yeast extract at a temperature below 17.5° c., antifoaming agent supplied up to 0.07%, agitation reduced to 400 rpm, and the induction phase extended out to 163 h.. .
|Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto|
Pyrazole derivatives of formula (ia) and pharmaceutical compositions thereof that modulate the activity of the serotonin 5ht2a receptor. Formula (ia).
|Containers for agitation of liquid samples and methods of use thereof|
The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample.