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Adverse Event

Adverse Event-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Article of manufacture comprising aflibercept or ziv-aflibercept
Sanofi
March 22, 2018 - N°20180078496

Article of manufacture comprising a packaging material, a polypeptide of seq id no:1, aflibercept or ziv-aflibercept or a biosimilar thereof, and a label comprising a printed statement which informs a prospective user of adverse events or adverse reactions.
Cardiac glycosides to reduce pulmonary exacerbations and other adverse events in cystic fibrosis and other ...
March 08, 2018 - N°20180064730

A small molecule inhibitor for treating a disorder in mammals, wherein the disorder is characterized by high levels of inflammatory components. In a preferred embodiment, the inhibitor comprises cardiac glycosides, also known as cardiac cardenolides. In one example, the drug digitoxin is used to treat the disorder cystic fibrosis. The compounds and methods of the invention are particularly effective for ...
Prognosis of adverse events in patients with suspected chronic heart failure
B.r.a.h.m.s. Gmbh
December 28, 2017 - N°20170370940

The present invention is in the field of clinical diagnostics. Particularly the present invention relates to the prognosis of adverse events in patients with stable chronic heart failure or being suspected of having stable chronic heart failure by determination of the level of procalcitonin (pct).
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Bolus dose of hydroxycitric acid with glycerol
Glykon Technologies Group, Llc
December 28, 2017 - N°20170368008

A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of active delivered via two or three administrations (b. I. D. Or t. I. D.) using current delivery modalities. The method reduces the rate of occurrence of common adverse ...
Event detection in an implantable auditory prosthesis
November 30, 2017 - N°20170340883

Presented herein are techniques for monitoring the physical state of a stimulating assembly to, for example, detect the occurrence of an adverse event. More specifically, an elongate stimulating assembly comprising a plurality of longitudinally spaced contacts is at least partially implanted into a recipient. Electrical measurements are performed at one or more of the plurality of contacts and the electrical ...
Anti-leukocyte adhesion for the mitigation of potential adverse events caused by cd3-specific binding domains
Amgen Research (munich) Gmbh
November 16, 2017 - N°20170327581

The present invention relates in essence to a compound which decreases or inhibits the binding of mammalian t-cells to mammalian endothelial cells for use in a method of prophylaxis and/or amelioration and/or treatment of clinical adverse events caused by therapy which comprises re-directing of t-cells against target cells in a patient. Methods of treatment of patients having or ...
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Materials and methods for improving the effectiveness of immunomodulatory cancer therapy and related methodologies
October 19, 2017 - N°20170298440

The disclosure provides methods of improving the effectiveness of an immunomodulatory cancer therapy by selecting a patient population amenable to immunomodulatory cancer therapy and methods of selecting cancer patient populations amenable to immunomodulatory therapy by measuring t cell repertoire clonality as well as methods of selecting cancer patients at reduced risk of developing an adverse event in response to such ...
Risk evaluation and management strategy involving patient follow-ups relating to the use or discontinuation of ...
Alexion Pharmaceuticals, Inc.
September 28, 2017 - N°20170277835

This invention provides, inter alia, a complement-inhibitor-based treatment plan coupled with a risk evaluation and management strategy (“rems”) and a safety support program (“ssp”) for reinforcing the rems. The rems and spp are implemented using one or more computer devices with software tools programmed to enforce conditions of the rems and/or ...
Method and device for prediction and detection of adverse events in bedridden people
Reqbo Aps
August 31, 2017 - N°20170245799

Embodiments relates to a method and apparatus for risk stratification, monitoring, detection and prediction of adverse events in bedridden people. The method and apparatus can be used to prevent heath related conditions in people.
Hydrant monitoring system and method
Silversmith, Inc.
August 03, 2017 - N°20170216645

A device for detecting adverse events in a fire hydrant, the device comprising a housing configured to mount to an exterior of the fire hydrant, the housing having a surface in register with the exterior of the fire hydrant, the surface having an aperture therein, a cover enclosing the housing and mounted to the fire hydrant at the surface. The ...
Proximity awareness system for motor vehicles
Ridar Systems Llc
July 27, 2017 - N°20170213460

Various embodiments provide enhanced warnings of potential future adverse events (e. G., automobile crashes) by tracking the location and motion of multiple vehicles, and providing alerts or warnings to the drivers of such vehicles in the event that a risk of an adverse event is identified.
Seatbelt buckle system
July 20, 2017 - N°20170203715

A seatbelt buckle system for law enforcement use, wherein the female portion of the buckle is located at the end of a segment which is in a generally upright and readily-accessible position to assure the safe and expeditious restraint of an individual. The individual securing the occupant is advantageously less prone to adverse events such as unwanted contact with or ...
Pharmaceutical composition for preventing or treating skin rash
Dong-a University Research Foundation For Industry-academy Cooperation
July 20, 2017 - N°20170202917

Provided is a method for preventing or treating skin rash comprising administering to a subject in need thereof epidermal growth factor as an active ingredient. The skin rash includes a skin disorder caused by administering an epidermal growth factor receptor inhibitor, such as erlotinib, as an adverse event.
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Predicting drug-drug interactions and specific adverse events
International Business Machines Corporation
June 22, 2017 - N°20170177803

The present invention provides methods, systems and devices for drug-drug interaction and adverse event analysis. Chemical structures for one or more pairs of drugs are obtained from at least one of a user and a database. A chemical fingerprint is generated for each drug of the one or more pairs of drugs based on the chemical structure of the drug. ...
Drug efficacy analysis system and drug efficacy analysis method
Tokyo Women's Medical University
June 08, 2017 - N°20170161469

The present invention enables statistical analysis of medical practice data with a small number of samples. The following steps are included: a model creation step in which a patient's factor information that is factor information relating to occurrence of an adverse event and includes test values before medication is regression-analyzed and a transition of test value after medication is modeled; ...
Hospital operations system
Qwaltec, Llc
June 08, 2017 - N°20170161443

A hospital operations system is provided which centralizes, processes, prioritizes, and presents vast data generated by hospital systems and software applications and partially controls devices, alerts, and overall patient care within hospital systems for greater efficiency and provision of improved patient care, patient safety, and hospital efficiency beyond what currently exists. The hospital operations system capabilities are enabled via dedicated ...
Fail-safe lighting control system
June 01, 2017 - N°20170156189

A light fixture can include at least one light source, and at least one power supply that receives primary power, where the at least one power source generates final power using the primary power, where the at least one power supply delivers the final power to the at least one light source. The light fixture can also include a controller ...
Providing status of user devices during an adverse event
May 04, 2017 - N°20170127260

A method begins by an application server establishing information regarding a potentially adverse condition and determining group constraints for a group regarding the potentially adverse condition. The method continues with the application server selecting one or more user devices of a plurality of user devices affiliated with the group to produce selected user devices. The method continues with the application ...
Providing status of user devices during an adverse event
May 04, 2017 - N°20170127232

A method begins by a processing module identifying a geographic area of an adverse condition and identifying a user device of a plurality of user devices potentially associated with the identified geographic area. The method continues with the processing module issuing a safety notification to the user device, where the safety notification includes one or more of the identified geographic ...
Materials and methods for differential treatment of cancer
Serametrix Corporation
May 04, 2017 - N°20170121776

The present invention concerns differential therapeutic treatment of cancer patients based on prognostic antigen/antibody profiles used for predicting (prognosticating) a clinical response (efficacy) and/or adverse event to an immunotherapy for treatment of a malignancy in a subject, and for treating or delaying the onset or relapse of a malignancy in a subject.
Methods and systems for adverse event prediction using pump operating data
Heartware, Inc.
May 04, 2017 - N°20170119256

The present disclosure provides for each of a method of characterizing divergence of a monitored flow rate of blood through an implantable blood pump, and a method of predicting an upcoming adverse cardiac event using operating data of the blood pump, such as the characterized divergence data. Predicting an upcoming adverse cardiac event may be further based on similar operating ...
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